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126867

Chemical and biological effects of some mixtures of plant oils and Thymus vulgaris on liver diseases

Article

Last updated: 25 Dec 2024

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Abstract

Liver is the vital organ with a wide range of functions that can influence other body organs. Dietary components are essential for the healthy or diseased liver. Selected food plants can provide nutritional and medicinal support for liver diseases. Herbal and oil medicinal products are increasingly being used and many of them have shown promising potential for the treatment of liver diseases. The aim of this study is to investigate the protective role of thyme, olive oil and flaxseed oil on carbon tetrachloride CCl4 induced changes in liver enzymes of albino rats. Sixty adult male Albino rats weighing about 130±5 g were taken and divided into twelve groups, each with five rats. The first group is the control (-) and fed on normal diet for 10 weeks. The second group received subcutaneous injection with CCL4 in paraffin oil (50% v/v 2 ml/kg) twice per week for 2 weeks to induce chronic damage in the liver tissue and fed on normal diet (control +). Another experimental groups (n = 5/group) were fed a Commercial diet with different doses from thyme, flaxseed oil and olive oil for 10 weeks. There were a significant increase in the activities of serum ALT and AST in rats of the positive control group (+) as compared to negative control group (-) (P ≤ 0.05).While the protected groups with high doses of thyme (4,6,8,10,12) and olive oil and flaxseed oil  (3,5,7,9 ,11 ) recorded a significant decreased serum AST and ALT  enzyme compared to the low doses groups. Recommendations and Conclusion: High doses of thyme, olive oil, and flaxseed oil could ameliorate carbon tetrachloride (CCl4)-induced liver injury in rats, which. Suggesting that diet rich in flaxseed oil, olive oil and thyme might be a promising approach for the prevention of liver diseases.    

DOI

10.21608/ajbs.2020.126867

Keywords

thyme, olive oil, Flaxseed oil, CCl4, albino rats, liver enzymes, kidney functions, Lipid profile

Authors

First Name

Samah

Last Name

Ismael

MiddleName

-

Affiliation

Home Economic Dept., Faculty of Specific Education, Ain Shams Univ., Cairo, Egypt

Email

samahdr2@hotmail.com

City

Cairo, Egypt

Orcid

-

First Name

Abour

Last Name

Abdelrahman

MiddleName

-

Affiliation

Home Economic Dept., Faculty of Specific Education, Ain Shams Univ., Cairo, Egypt

Email

-

City

Cairo, EgyptCairo, Egypt

Orcid

-

First Name

Eman

Last Name

Sultan

MiddleName

-

Affiliation

Endocrinology and Metabolism Department, National Nutrition Institute, Egypt

Email

-

City

Cairo, Egypt

Orcid

-

First Name

Shaimaa

Last Name

Omran

MiddleName

M

Affiliation

Home Economic Dept., Faculty of Specific Education, Ain Shams Univ., Cairo, Egypt

Email

-

City

Cairo, Egypt

Orcid

-

Volume

16

Article Issue

1

Related Issue

10641

Issue Date

2020-12-01

Receive Date

2020-12-01

Publish Date

2020-12-01

Page Start

167

Page End

183

Print ISSN

1687-4870

Online ISSN

2314-5501

Link

https://ajbs.journals.ekb.eg/article_126867.html

Detail API

https://ajbs.journals.ekb.eg/service?article_code=126867

Order

13

Type

Original Article

Type Code

1,101

Publication Type

Journal

Publication Title

African Journal of Biological Sciences

Publication Link

https://ajbs.journals.ekb.eg/

MainTitle

Chemical and biological effects of some mixtures of plant oils and Thymus vulgaris on liver diseases

Details

Type

Article

Created At

22 Jan 2023