271822

IL-17F GENE POLYMORPHISM (7488T/C, RS763780) IN EGYPTIAN PATIENTS WITH SLE

Article

Last updated: 04 Jan 2025

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Abstract

Systemic Lupus erythematosus (SLE) is a worldwide autoimmune disease with different presentations. Genetic and environmental factors like infection and ultraviolet light are supposed to be responsible for the development of SLE. Disturbance in cytokines production may be involved in SLE pathogenesis. In this case-control study, we investigate the interleukin-17F (IL-17F) gene polymorphism (7488T/C, rs763780) in Egyptian SLE patients using polymerase chain reaction-restriction fragment length polymorphism (PCR–RFLP). There were no significant changes when both genotypes and alleles for patients and controls were compared with each other. According to the results, no association between the IL-17F gene polymorphism (7488T/C, rs763780) and SLE.
 

DOI

10.21608/bfsa.2022.271822

Keywords

SLE, IL-17F, cytokine, Autoimmune

Authors

First Name

Sherif

Last Name

ElSherbini

MiddleName

-

Affiliation

Molecular Biology Department, Genetic Engineering and Biotechnology Institute, Sadat City University, Egypt

Email

firstsherif_2000@yahoo.com

City

-

Orcid

-

First Name

Abada

Last Name

AbdAlRaouf

MiddleName

-

Affiliation

Molecular Biology Department, Genetic Engineering and Biotechnology Institute, Sadat City University, Egypt

Email

-

City

-

Orcid

-

First Name

Samir

Last Name

El-Masry

MiddleName

-

Affiliation

Molecular Biology Department, Genetic Engineering and Biotechnology Institute, Sadat City University, Egypt

Email

samirelmasry74@yahoo.com

City

-

Orcid

-

First Name

Adel

Last Name

Abdelsalam

MiddleName

-

Affiliation

Internal Medicine Department, Rheumatology & Immunology Unit, Mansoura Faculty of Medicine, Mansoura University, Egypt

Email

adel_abdelsallam_2013@yahoo.com

City

-

Orcid

-

First Name

Maged

Last Name

Mostafa

MiddleName

-

Affiliation

Clinical Pathology Department, Faculty of Medicine, Mansoura University, Egypt

Email

magedmostafa1981@gmail.com

City

-

Orcid

0000-0001-9723-2710

Volume

45

Article Issue

2

Related Issue

37882

Issue Date

2022-12-01

Receive Date

2022-05-31

Publish Date

2022-12-01

Page Start

1,085

Page End

1,096

Print ISSN

1110-0052

Online ISSN

3009-7703

Link

https://bpsa.journals.ekb.eg/article_271822.html

Detail API

https://bpsa.journals.ekb.eg/service?article_code=271822

Order

271,822

Type

Original Article

Type Code

1,096

Publication Type

Journal

Publication Title

Bulletin of Pharmaceutical Sciences Assiut University

Publication Link

https://bpsa.journals.ekb.eg/

MainTitle

IL-17F GENE POLYMORPHISM (7488T/C, RS763780) IN EGYPTIAN PATIENTS WITH SLE

Details

Type

Article

Created At

22 Jan 2023