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271791

EVALUATION OF SERUM ZINC LEVELS AND ITS RELATIONSHIP TO GLYCEMIC CONTROL AND LIPID PROFILE IN TYPE (2) DIABETES MELLITUS

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Last updated: 25 Dec 2024

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Abstract

Due to the importance of Zinc in glucose and lipid metabolism, it has been aimed in this study to investigate the association of serum zinc levels with glycemic control and lipid profile in type 2 diabetes mellitus patients (T2DM). This study has been conducted on 129 adult patients with diabetes at Tishreen University Hospital (TUH) and The Diabetes Center of Latakia City in Syria, and 51 matched healthy subjects. The results have shown a statistically significant decrease in serum zinc levels in T2DM patients compared with controls. A statistically significant negative correlation has been identified between zinc and all of HbA1C, BMI, duration of disease, and triglycerides, while a positive correlation has been observed with HDL levels in the diabetic group. In conclusion, this study has demonstrated that low zinc level is associated with poor glycemic control and it may give a cause to explain a possible association with dyslipidemia observed in T2DM patients.
 
 

DOI

10.21608/bfsa.2022.271791

Keywords

 Type 2 Diabetes Mellitus,   Serum Zinc, Glycemic control, dyslipidemia

Authors

First Name

Hla

Last Name

Sudan

MiddleName

-

Affiliation

Department of Biochemistry and Microbiology, Faculty of Pharmacy, Tishreen University, Lattakia, Syria

Email

hlasudan@gmail.com

City

-

Orcid

-

First Name

Remal

Last Name

Asaad

MiddleName

-

Affiliation

Department of Biochemistry and Microbiology, Faculty of Pharmacy, Tishreen University, Lattakia, Syria

Email

rimalasaad@tishreen.edu.sy

City

-

Orcid

-

Volume

45

Article Issue

2

Related Issue

37882

Issue Date

2022-12-01

Receive Date

2022-03-26

Publish Date

2022-12-01

Page Start

1,051

Page End

1,061

Print ISSN

1110-0052

Online ISSN

3009-7703

Article File

BFSA_Volume 45_Issue 2_Pages 1051-1061.pdf

PDF . 1.0MB

Link

https://bpsa.journals.ekb.eg/article_271791.html

Detail API

https://bpsa.journals.ekb.eg/service?article_code=271791

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271,791

Type

Original Article

Type Code

1,096

Publication Type

Journal

Publication Title

Bulletin of Pharmaceutical Sciences Assiut University

Publication Link

https://bpsa.journals.ekb.eg/

MainTitle

EVALUATION OF SERUM ZINC LEVELS AND ITS RELATIONSHIP TO GLYCEMIC CONTROL AND LIPID PROFILE IN TYPE (2) DIABETES MELLITUS

Details

Type

Article

Created At

22 Jan 2023