Beta
ManageSearchChatDiscover
271581

PROSPECT OF NATURAL COMPOUNDS AGAINST MALARIA: A REVIEW

Article

Last updated: 25 Dec 2024

OverviewSimilar Items

Subjects

-

Tags

-

Abstract

Malaria is one of the leading life-threatening vectors borne diseases prevalent in tropical and subtropical regions of the world. The traditional system of medicine uses drugs of plant origin. Quinine and artemisinin, two naturally occurring plant chemicals, are traditionally used to treat malaria. The present reviews have emphasized the anti-malarial activity of plants that are effective against emerging resistance. The aim of the present study was to analyze the concept and objectives of isolated natural compounds, their mechanism of action, and plant parts used for malaria treatment in the traditional system of medicine. 113 isolated compounds, plant parts used from 49 species, and molecular mechanism of 70 anti-malarial natural compounds from various plant species were explored. These plants were traditionally used for malaria treatment worldwide. They are therapeutically more effective, safer, and traditionally reported for having high cure rates. There is an urgent need for the development of novel drugs to treat malaria. These isolated compounds may be explored for the development of antimalarial drugs against plasmodium-resistant strains.

DOI

10.21608/bfsa.2022.271581

Keywords

Anti-malarial, Natural compounds, Chemical nature, medicinal plants

Authors

First Name

Tarsem

Last Name

Nain

MiddleName

-

Affiliation

Department of Genetics, Maharshi Dayanand University, Rohtak-124001, Haryana, India

Email

tarsemnain88@gmail.com

City

-

Orcid

-

First Name

Shammi

Last Name

Sharma

MiddleName

-

Affiliation

Department of Genetics, Maharshi Dayanand University, Rohtak-124001, Haryana, India

Email

shammisharma0003@gmail.com

City

-

Orcid

-

First Name

Neha

Last Name

Chawariya

MiddleName

-

Affiliation

Department of Genetics, Maharshi Dayanand University, Rohtak-124001, Haryana, India

Email

chawariyane243@gmail.com

City

-

Orcid

-

First Name

Jaya Parkash

Last Name

Yadav

MiddleName

-

Affiliation

Department of Genetics Maharshi Dayanand University Rohtak

Email

yadav1964@rediffmail.com

City

Rohtak

Orcid

0000-0002-3500-6811

Volume

45

Article Issue

2

Related Issue

37882

Issue Date

2022-12-01

Receive Date

2022-04-30

Publish Date

2022-12-01

Page Start

629

Page End

653

Print ISSN

1110-0052

Online ISSN

3009-7703

Article File

BFSA_Volume 45_Issue 2_Pages 629-653.pdf

PDF . 1.3MB

Link

https://bpsa.journals.ekb.eg/article_271581.html

Detail API

https://bpsa.journals.ekb.eg/service?article_code=271581

Order

271,581

Type

Original Article

Type Code

1,096

Publication Type

Journal

Publication Title

Bulletin of Pharmaceutical Sciences Assiut University

Publication Link

https://bpsa.journals.ekb.eg/

MainTitle

PROSPECT OF NATURAL COMPOUNDS AGAINST MALARIA: A REVIEW

Details

Type

Article

Created At

22 Jan 2023