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271489

PHYTOCHEMICAL SCREENING AND PHARMAOCOLOGICAL EVALUATION OF TECOMA GAUDICHAUDI

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Last updated: 04 Jan 2025

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Abstract

Tecoma gaudichaudi is a tropical flowering plant in the Bignoniaceae family that is used to treat diabetes. The aim of this research was to evaluate antioxidant, anti-inflammatory, and antibacterial properties. Tecoma gaudichaudi ethanolic extract had considerable antioxidant activity. Antioxidant activity was measured using the DPPH assay, the radical scavenging method, and the superoxide assay. Antibacterial activity and antifungal activity were performed by cup plate method by using Ciprofloxacin as standard for antibacterial and antifungal activity. Ethanolic extract of Tecomo gaudichaudi shows significant antibacterial effect against S. Aureus, B. Subtilis, P. vulgaris and E. coli using ciprofloxacin (50µg/ml) as standard. Three alternative methods were used to calculate IC50 values for antioxidant activity. The IC50 values for T. gaudichaudi (21 g/ml) and ascorbic acid (12 g/ml) were obtained using the DPPH technique. For anti-inflammatory studies the extracts show remarkable zone of inhibition ranging from 58.97 to 72.35 µg/ml respectively compared to standard indomethacin. Steroids, saponins, flavonoids, triterpenes, and phenols are found in preliminary phytochemical investigation. In conclusion, ethanolic extract of Tecomo gaudichaudi shows significant antioxidant, anti-inflammatory and antibacterial properties.

DOI

10.21608/bfsa.2022.271489

Keywords

DPPH, Hydroxy radical scavenging, Antibacterial, Anti-inflammatory, Tecoma gaudichaudi

Authors

First Name

Alekhya

Last Name

Veeramaneni

MiddleName

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Affiliation

Department of Pharmacognosy GIET School of Pharmacy Rajahmundry

Email

alekhya.veramaneni@gmail.com

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First Name

T.

Last Name

Deepan

MiddleName

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Affiliation

Department of Pharmacognosy, GIET School of Pharmacy, NH-16, Chaitanya knowledge city, Rajamahendravaram-533296, Andhrapradesh, India

Email

-

City

-

Orcid

-

First Name

S.

Last Name

Ganapaty

MiddleName

-

Affiliation

Department of Pharmacognosy, GITAM Institute of Pharmacy, Gandhinagar, Rushikonda, Visakhapatnam-530045, Andhrapradesh, India

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-

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Volume

45

Article Issue

2

Related Issue

37882

Issue Date

2022-12-01

Receive Date

2022-02-03

Publish Date

2022-12-01

Page Start

585

Page End

592

Print ISSN

1110-0052

Online ISSN

3009-7703

Article File

BFSA_Volume 45_Issue 2_Pages 585-592.pdf

PDF . 859.6kB

Link

https://bpsa.journals.ekb.eg/article_271489.html

Detail API

https://bpsa.journals.ekb.eg/service?article_code=271489

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271,489

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Original Article

Type Code

1,096

Publication Type

Journal

Publication Title

Bulletin of Pharmaceutical Sciences Assiut University

Publication Link

https://bpsa.journals.ekb.eg/

MainTitle

PHYTOCHEMICAL SCREENING AND PHARMAOCOLOGICAL EVALUATION OF TECOMA GAUDICHAUDI

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Article

Created At

22 Jan 2023