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INFLAMMATORY STATUS IN WOMEN WITH POLYCYSTIC OVARIAN SYNDROME IN GAZA STRIP

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Last updated: 04 Jan 2025

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Abstract

 
Polycystic ovary syndrome (PCOS) is a hormonal disorder that is common among women of childbearing age. The study aimed to evaluate the inflammatory status among women with PCOS in Gaza Strip by measuring C-reactive protein (CRP) concentration and white blood cell (WBC) count in women participating in the study. 180 women were selected from gynecologic private clinics in Gaza Strip were divided into three groups: healthy control group (n= 60); newly diagnosed PCOS group (n= 60); treated PCOS group (n= 60). Our results showed significant differences in the mean concentrations of FPG, FPI, FSH, and LH in the newly diagnosed PCOS patients compared with the healthy subjects as well as the treated PCOS patients. We also observed a significant increase in CRP concentrations and WBC count in the newly diagnosed PCOS patients compared with the healthy controls (p-value< 0.001, < 0.01 respectively) as well as the treated PCOS patients (p-value< 0.01, < 0.05 respectively). In conclusion, these findings suggest that PCOS can increase insulin resistance among PCOS women which may play a role in the inflammation process among PCOS women.

DOI

10.21608/bfsa.2022.239467

Keywords

polycystic ovary syndrome, Insulin Resistance, Inflammatory mediators

Authors

First Name

Mohammed

Last Name

Taha

MiddleName

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Affiliation

Department of Pharmacology and Medical Sciences, Faculty of Pharmacy, Al-Azhar University of Gaza, Gaza, Palestine

Email

m.taha@alazhar.edu.ps

City

-

Orcid

0000-0001-9350-2111

Volume

45

Article Issue

1

Related Issue

34403

Issue Date

2022-06-01

Receive Date

2021-11-05

Publish Date

2022-06-01

Page Start

289

Page End

297

Print ISSN

1110-0052

Online ISSN

3009-7703

Article File

BFSA_Volume 45_Issue 1_Pages 289-297.pdf

PDF . 675.0kB

Link

https://bpsa.journals.ekb.eg/article_239467.html

Detail API

https://bpsa.journals.ekb.eg/service?article_code=239467

Order

23

Type

Original Article

Type Code

1,096

Publication Type

Journal

Publication Title

Bulletin of Pharmaceutical Sciences Assiut University

Publication Link

https://bpsa.journals.ekb.eg/

MainTitle

INFLAMMATORY STATUS IN WOMEN WITH POLYCYSTIC OVARIAN SYNDROME IN GAZA STRIP

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Type

Article

Created At

22 Jan 2023