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174143

INFLUENCE OF DIFFERENT RESTORATIVE MATERIALS ON THE SENSITIVITY OF STREPTOCOCCUS MUTANS BIOFILM TO DIFFERENT ANTIMICROBIAL MOUTHRINSES IN-VITRO

Article

Last updated: 25 Dec 2024

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Abstract

Objectives: The aim of this study was to assess the antibacterial effects of chlorhexidine gluconate, sodium fluoride, and sodium fluoride-xylitol combination mouthrinses on S. mutans biofilm in-vitro, and most significantly, we aimed to compare different restorative materials regarding the sensitivity of S. mutans biofilms formed on their surfaces to the antibacterial effects of the tested mouthrinses. Results: Chlorhexidine gluconate 0.12%, sodium fluoride 0.05%, and sodium fluoride 0.05% - xylitol 25% combination exhibited statistically significant antibacterial effects on S. mutans biofilm. The addition of xylitol 25% to sodium fluoride 0.05% mouthrinse was associated with higher antibacterial effects compared with sodium fluoride alone. S. mutans biofilms formed on GIC specimens exhibited the highest sensitivity to antibacterial treatments, whereas biofilms formed on stainless steel specimens showed the lowest sensitivity. Conclusion: S. mutans biofilms formed on different restorative materials exhibited different sensitivity levels to antimicrobial mouthrinses.

DOI

10.21608/bfsa.2021.174143

Authors

First Name

Nermin

Last Name

Al-Agha

MiddleName

-

Affiliation

Department of Biochemistry and Microbiology, Faculty of Pharmacy, Damascus University, Damascus, Syria

Email

nermin.s.agha@gmail.com

City

-

Orcid

-

First Name

Mostafa

Last Name

Al-Ammori

MiddleName

-

Affiliation

Department of Biochemistry and Microbiology, Faculty of Pharmacy, Damascus University, Damascus, Syria

Email

ammori@scs-net.org

City

-

Orcid

-

First Name

Chaza

Last Name

Koushaji

MiddleName

-

Affiliation

Professor in Pediatric Dentistry, Faculty of Dentistry, Damascus University, Damascus, Syria

Email

shazako@yahoo.com

City

-

Orcid

-

Volume

44

Article Issue

1

Related Issue

25283

Issue Date

2021-06-01

Receive Date

2020-11-06

Publish Date

2021-06-01

Page Start

173

Page End

184

Print ISSN

1110-0052

Online ISSN

3009-7703

Article File

BFSA_Volume 44_Issue 1_Pages 173-184.pdf

PDF . 723.8kB

Link

https://bpsa.journals.ekb.eg/article_174143.html

Detail API

https://bpsa.journals.ekb.eg/service?article_code=174143

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17

Type

Original Article

Type Code

1,096

Publication Type

Journal

Publication Title

Bulletin of Pharmaceutical Sciences Assiut University

Publication Link

https://bpsa.journals.ekb.eg/

MainTitle

INFLUENCE OF DIFFERENT RESTORATIVE MATERIALS ON THE SENSITIVITY OF STREPTOCOCCUS MUTANS BIOFILM TO DIFFERENT ANTIMICROBIAL MOUTHRINSES IN-VITRO

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Article

Created At

22 Jan 2023