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127401

PHYTOCHEMICAL AND BIOLOGICAL STUDY OF CENTAUREA CINERARIA L. CULTIVATED IN SYRIA

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Last updated: 25 Dec 2024

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Abstract

In the current study, C. cineraria plant was subjected to chemical and biological study. The plant extract was screened for its phytochemical constituents, its quantitative content of phenolics, and its activity in scavenging free radical (DPPH). The plant was subjected to a biological study, which includes investigating the potential cytotoxic effect of the plant towards human erythrocytes membranes, and the ability of the plant to protect erythrocytes against oxidative hemolysis. The results indicated that the extract did not contain saponins. Our study also showed that the extract contains a good content of phenolics (41.12±0.6) mg GAE/g, and has good DPPH radical scavengingactivity (79.96%±1.14). The results showed that the extract does not have a toxic effect on erythrocytes membranes, and it is highly effective in protecting the membranes from oxidative damage (IC50 value was 408.86 μg/ml). We hope that future studies will focus on the pharmaceutical aspects of this plant, and will not be considered as ornamental plant only.

DOI

10.21608/bfsa.2020.127401

Authors

First Name

R.

Last Name

Joujeh

MiddleName

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Affiliation

Department of Plant Biology, Damascus University, Damascus, Syria

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Volume

43

Article Issue

2

Related Issue

19039

Issue Date

2020-12-01

Receive Date

2020-08-05

Publish Date

2020-12-01

Page Start

141

Page End

147

Print ISSN

1110-0052

Online ISSN

3009-7703

Article File

BFSA_Volume 43_Issue 2_Pages 141-147.pdf

PDF . 421.5kB

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https://bpsa.journals.ekb.eg/article_127401.html

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https://bpsa.journals.ekb.eg/service?article_code=127401

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Original Article

Type Code

1,096

Publication Type

Journal

Publication Title

Bulletin of Pharmaceutical Sciences Assiut University

Publication Link

https://bpsa.journals.ekb.eg/

MainTitle

PHYTOCHEMICAL AND BIOLOGICAL STUDY OF CENTAUREA CINERARIA L. CULTIVATED IN SYRIA

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Article

Created At

22 Jan 2023