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PRELIMINARY PHYTOCHEMICAL INVESTIGATION AND IN-VITRO ANTIDIABETIC ACTIVITY OF AN AYURVEDIC FORMULATION

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Last updated: 25 Dec 2024

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Abstract

Objective: To carry out the preliminary phytochemical analysis and to perform the in-vitro anti diabetic activity for the ayurvedic poly herbal formulation. Material and Methods: Preliminary phytochemical analysis was performed as per the standard procedures. In-vitro anti-diabetic activity was done by two methods namely alpha amylase inhibitory assay and alpha glucosidase inhibitory assay by taking acarbose as a standard drug for the ayurvedic formulation. Statistical analysis is carried out by means of graphpad prism software version 6. Results and conclusion: Preliminary phytochemical analysis showed the presence of alkaloids, glycosides, phytosterols, phenols, flavonoids and terpenoids in the formulation. The poly herbal tablet produced 32.2% inhibition of alpha amylase activity at a concentration of 125 µg/ml and 80.8% inhibition of alpha glucosidase activity at a concentration of 62.5 µg/ml. The present study shows that the selected ayurvedic poly herbal tablets has an anti-diabetic activity comparable with that of allopathic drug - acarbose tablet.

DOI

10.21608/bfsa.2020.127400

Authors

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S.

Last Name

Gayatri

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Affiliation

Assistant Professor, Sri Ramachandra Faculty of Pharmacy, SRIHER (DU), Porur, Chennai-600116, Tamil Nadu, India

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Orcid

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First Name

V.

Last Name

Monica

MiddleName

Angel Seslin

Affiliation

Student, Sri Ramachandra Faculty of Pharmacy, SRIHER (DU), Porur, Chennai-600116, Tamil Nadu, India

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Volume

43

Article Issue

2

Related Issue

19039

Issue Date

2020-12-01

Receive Date

2020-07-04

Publish Date

2020-12-01

Page Start

135

Page End

139

Print ISSN

1110-0052

Online ISSN

3009-7703

Article File

BFSA_Volume 43_Issue 2_Pages 135-139.pdf

PDF . 429.4kB

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https://bpsa.journals.ekb.eg/article_127400.html

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https://bpsa.journals.ekb.eg/service?article_code=127400

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Original Article

Type Code

1,096

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Journal

Publication Title

Bulletin of Pharmaceutical Sciences Assiut University

Publication Link

https://bpsa.journals.ekb.eg/

MainTitle

PRELIMINARY PHYTOCHEMICAL INVESTIGATION AND IN-VITRO ANTIDIABETIC ACTIVITY OF AN AYURVEDIC FORMULATION

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Article

Created At

22 Jan 2023