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104853

COLORIMETRIC DETERMINATION OF CERTAIN SYMPATHOMIMETIC DRUGS

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Last updated: 25 Dec 2024

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Abstract

A rapid, simple and highly sensitive spectrophotometric method for the determination of oxiderine tartrate, etilefrine hydrochloride, metaraminol bitartrate, orciprenaline sulphate and isoprenaline sulphate is described. The method depends on the reaction of aqueous solution of these drugs with the diazotized 5-chloro-2,4-dinitroaniline in alkaline medium to give a highly coloured product with characteristic lmax for each drug in the range of 420-550 nm. The colour produced in all cases obeys Beer's law. This method is suitable for the analysis of these drugs in pure forms and in pharmaceutical preparations without prior separation.

DOI

10.21608/bfsa.1979.104853

Authors

First Name

Salwa

Last Name

El-Shabouri

MiddleName

R.

Affiliation

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt

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Orcid

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Volume

2

Article Issue

1

Related Issue

15889

Issue Date

1979-12-01

Publish Date

1979-12-31

Page Start

77

Page End

89

Print ISSN

1110-0052

Online ISSN

3009-7703

Article File

BFSA_Volume 2_Issue 1_Pages 77-89.pdf

PDF . 458.9kB

Link

https://bpsa.journals.ekb.eg/article_104853.html

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https://bpsa.journals.ekb.eg/service?article_code=104853

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Type

Original Article

Type Code

1,096

Publication Type

Journal

Publication Title

Bulletin of Pharmaceutical Sciences Assiut University

Publication Link

https://bpsa.journals.ekb.eg/

MainTitle

COLORIMETRIC DETERMINATION OF CERTAIN SYMPATHOMIMETIC DRUGS

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Article

Created At

22 Jan 2023