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104849

A STUDY ON THE SOLUBILITY AND STABILITY OF ETHINYL OESTRADIOL

Article

Last updated: 25 Dec 2024

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Abstract

Atrial was made to prepare solutions of ethinyl oestradiol by series of selected surfactants. It was found that the cationic surfactant was the best solubilizer for this hormone followed by the anionic then the non-ionic ones. The solubilized systems were further investigated for their stability under different storage conditions. It was noticed that the solutions prepared by non-ionic surfactants gave rise to the most stable preparation for this hormone, especially in the presence of antioxidants and preservatives. Storage of this preparation in amber coloured ampoules at 5° was also desirable, as it can keep its potency for a period up to 6 months.

DOI

10.21608/bfsa.1979.104849

Authors

First Name

H.

Last Name

El-Sabbagh

MiddleName

M.

Affiliation

Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt

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Orcid

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First Name

A.

Last Name

Aboutaleh

MiddleName

E.

Affiliation

Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt

Email

-

City

-

Orcid

-

First Name

A.

Last Name

Sakr

MiddleName

M.

Affiliation

Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt

Email

-

City

-

Orcid

-

First Name

M.

Last Name

Abdel-Hake

MiddleName

-

Affiliation

Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt

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Volume

2

Article Issue

1

Related Issue

15889

Issue Date

1979-12-01

Publish Date

1979-12-31

Page Start

41

Page End

58

Print ISSN

1110-0052

Online ISSN

3009-7703

Article File

BFSA_Volume 2_Issue 1_Pages 41-58.pdf

PDF . 593.0kB

Link

https://bpsa.journals.ekb.eg/article_104849.html

Detail API

https://bpsa.journals.ekb.eg/service?article_code=104849

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Type

Original Article

Type Code

1,096

Publication Type

Journal

Publication Title

Bulletin of Pharmaceutical Sciences Assiut University

Publication Link

https://bpsa.journals.ekb.eg/

MainTitle

A STUDY ON THE SOLUBILITY AND STABILITY OF ETHINYL OESTRADIOL

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Article

Created At

22 Jan 2023