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104722

QUINAZOLINONE DERIVATIVES OF BIOLOGICAL INTEREST. II. SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF CERTAIN 3-ARYL-2-(-ARYLSULPHONYLHYDRAZINOMETHY-4(3H)-QUINAZOLINONES

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Last updated: 25 Dec 2024

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Abstract

Twenty five new quinazolinone derivatives were synthesized. Structure of these compounds was established by microanalysis, UV and IR spectrometry, Antibacterial activity of the prepared compounds was determined in comparison to sulphanilamide against four microorganisms. Fifteen compounds exhibited measurable antibacterial activity especially towards Staph. aureus.

DOI

10.21608/bfsa.1980.104722

Authors

First Name

A.

Last Name

Abdel-Aleem

MiddleName

M.

Affiliation

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt

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First Name

A.

Last Name

Abdel-Ghaffer

MiddleName

F.

Affiliation

Department of Microbiology, Faculty of Medicine, Assiut University, Assiut, Egypt

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Volume

3

Article Issue

1

Related Issue

15863

Issue Date

1980-12-01

Publish Date

1980-12-31

Page Start

116

Page End

124

Print ISSN

1110-0052

Online ISSN

3009-7703

Article File

BFSA_Volume 3_Issue 1_Pages 116-124.pdf

PDF . 294.5kB

Link

https://bpsa.journals.ekb.eg/article_104722.html

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https://bpsa.journals.ekb.eg/service?article_code=104722

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Original Article

Type Code

1,096

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Journal

Publication Title

Bulletin of Pharmaceutical Sciences Assiut University

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https://bpsa.journals.ekb.eg/

MainTitle

QUINAZOLINONE DERIVATIVES OF BIOLOGICAL INTEREST. II. SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF CERTAIN 3-ARYL-2-(-ARYLSULPHONYLHYDRAZINOMETHY-4(3H)-QUINAZOLINONES

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Article

Created At

22 Jan 2023