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104720

EFFECT OF DIFFERENT ADDITIVES ON THE MICELLAR SOLUBILIZATION OF CHLORAMPHENICOL

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Last updated: 25 Dec 2024

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Abstract

The effect of different inorganic and organic additives on the solubility of chloramphenicol by non-ionic surfactant solutions was investigated at two different temperatures. The following additives were used namely polyethylene glycol 600, propylene glycol, glycerol, urea and potassium chloride. Urea produced a slight effect on the solubilizing efficiency of the non-ionic surfactant solutions; on the other hand a more pronounced effect on the solubilizing efficiency of these nonionic micelles was obtained by increasing the concentration of potassium chloride in solutions. For organic additives it was found that the addition of polyethylene glycol 600 increased the solubilizing efficiency of all the non-ionic surfactant solutions than both glycerol and propylene glycol.

DOI

10.21608/bfsa.1980.104720

Authors

First Name

A.

Last Name

Aboutaleb

MiddleName

E.

Affiliation

Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt

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Orcid

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First Name

A.

Last Name

Abdelzaher

MiddleName

-

Affiliation

Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt

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-

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Volume

3

Article Issue

1

Related Issue

15863

Issue Date

1980-12-01

Publish Date

1980-12-31

Page Start

87

Page End

104

Print ISSN

1110-0052

Online ISSN

3009-7703

Link

https://bpsa.journals.ekb.eg/article_104720.html

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https://bpsa.journals.ekb.eg/service?article_code=104720

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8

Type

Original Article

Type Code

1,096

Publication Type

Journal

Publication Title

Bulletin of Pharmaceutical Sciences Assiut University

Publication Link

https://bpsa.journals.ekb.eg/

MainTitle

EFFECT OF DIFFERENT ADDITIVES ON THE MICELLAR SOLUBILIZATION OF CHLORAMPHENICOL

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Article

Created At

22 Jan 2023