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104593

APPLICATION OF DIALYSIS UNDER PRESSURE FOR INVESTIGATING THE INTERACTION BETWEEN CHLORAMPHENICOL AND NON-IONIC SURFACTANTS

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Last updated: 04 Jan 2025

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Abstract

Ultrafiltration technique was applied for investigating undersaturated systems containing chloramphenicol using Diaflo membrane UM 05. This drug was solubilized by a series of non-ionic surfactants which include Tween 20, Tween 40, Tween 60, Tween 80, Emulgin C1000, Emulgin C1500, Myrj 52, Myrj 53 and Myrj 59, at two different temperatures. It was found that the amount of chloramphenicol bound to the micelles as calculated from the ultrafiltration experiments was greater for Emulgin C1000, than Emulgin C1500 on the other hand the binding capacity of the different Tweens for chloramphenicol can be arranged as follows: Tween 80 > Tween 40 > Tween 60 > Tween 20. For Myrj series, Myrj 52 was found to be greater than Myrj 53 and both were higher than Myrj 59.

DOI

10.21608/bfsa.1981.104593

Authors

First Name

A.

Last Name

Aboutaleb

MiddleName

E.

Affiliation

Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt

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Orcid

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First Name

A.

Last Name

Abdelzaher

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Affiliation

Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt

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Volume

4

Article Issue

1

Related Issue

15861

Issue Date

1981-12-01

Publish Date

1981-12-31

Page Start

120

Page End

132

Print ISSN

1110-0052

Online ISSN

3009-7703

Article File

BFSA_Volume 4_Issue 1_Pages 120-132.pdf

PDF . 361.0kB

Link

https://bpsa.journals.ekb.eg/article_104593.html

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https://bpsa.journals.ekb.eg/service?article_code=104593

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9

Type

Original Article

Type Code

1,096

Publication Type

Journal

Publication Title

Bulletin of Pharmaceutical Sciences Assiut University

Publication Link

https://bpsa.journals.ekb.eg/

MainTitle

APPLICATION OF DIALYSIS UNDER PRESSURE FOR INVESTIGATING THE INTERACTION BETWEEN CHLORAMPHENICOL AND NON-IONIC SURFACTANTS

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Article

Created At

22 Jan 2023