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102097

FORMULATION AND IN-VITRO EVALUATION OF RIBOFLAVIN TABLETS PREPARED BY FLUIDIZED BED GRANULATION TECHNIQUE

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Last updated: 04 Jan 2025

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Abstract

Spray granulation technique using fluidized bed was used for preparing riboflavin granules. Five binders were used for granulation as spray liquids, Polyvinylpyrrolidone proved to be the most suitable binder followed by sodium alginate and sodium carboxy methyl cellulose. Methyl cellulose produced tablets which disintegrated within the U.S.P.XX. Limit, but of low dissolution rate; while ethyl cellulose gave tablets which did not conform to the official Limit, but the drug was released from the tablet matrix faster than from tablets prepared by methyl cellulose.

DOI

10.21608/bfsa.1983.102097

Authors

First Name

M.

Last Name

Kassem

MiddleName

A. A.

Affiliation

Department of Pharmaceutics, Faculty of Pharmacy, Cairo University, Cairo, Egypt

Email

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City

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Orcid

-

First Name

A.

Last Name

Nouh

MiddleName

T.

Affiliation

Department of Pharmaceutics, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt

Email

-

City

-

Orcid

-

First Name

T.

Last Name

El-Bayomy

MiddleName

-

Affiliation

National Organization for Drug and Research, Giza, Egypt

Email

-

City

-

Orcid

-

First Name

Alaa

Last Name

Kassem

MiddleName

A. A.

Affiliation

Department of Pharmaceutics, Faculty of Pharmacy, El-Azhr University, Nasr City, Cairo, Egypt

Email

-

City

-

Orcid

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Volume

6

Article Issue

2

Related Issue

15457

Issue Date

1983-12-01

Receive Date

1982-11-25

Publish Date

1983-12-31

Page Start

387

Page End

398

Print ISSN

1110-0052

Online ISSN

3009-7703

Article File

BFSA_Volume 6_Issue 2_Pages 387-398.pdf

PDF . 344.4kB

Link

https://bpsa.journals.ekb.eg/article_102097.html

Detail API

https://bpsa.journals.ekb.eg/service?article_code=102097

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11

Type

Original Article

Type Code

1,096

Publication Type

Journal

Publication Title

Bulletin of Pharmaceutical Sciences Assiut University

Publication Link

https://bpsa.journals.ekb.eg/

MainTitle

FORMULATION AND IN-VITRO EVALUATION OF RIBOFLAVIN TABLETS PREPARED BY FLUIDIZED BED GRANULATION TECHNIQUE

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Article

Created At

22 Jan 2023