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102092

EFFECT OF PH, TEMPERATURE AND CERTAIN ADDITIVES ON THE SOLUBILIZATION OF CARBAMAZEPINE BY SELECTED NON-IONIC SURFACTANT SOLUTIONS

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Last updated: 04 Jan 2025

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Abstract

The effect of incorporation of various organic additives on the solvent power of the different micelles for Carbamazepine was investigated. The variation in the pH value as well as the temperature of these solution on the degree of solubilization of Carbamazepine was also studied. It was found that propylene glycol increased the solvent power of the different micelles, while glycerol, and PEG 1000, 4000 and 6000 decrease their solubilizing capacity. Raising the temperature and lowering of pH value also increased the solvent power of the micelles.

DOI

10.21608/bfsa.1983.102092

Authors

First Name

A.

Last Name

Aboutaleb

MiddleName

E.

Affiliation

Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt

Email

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City

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Orcid

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First Name

S.

Last Name

Ahmed

MiddleName

M.

Affiliation

Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt

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-

City

-

Orcid

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Volume

6

Article Issue

2

Related Issue

15457

Issue Date

1983-12-01

Receive Date

1982-10-20

Publish Date

1983-12-31

Page Start

321

Page End

334

Print ISSN

1110-0052

Online ISSN

3009-7703

Article File

BFSA_Volume 6_Issue 2_Pages 321-334.pdf

PDF . 496.9kB

Link

https://bpsa.journals.ekb.eg/article_102092.html

Detail API

https://bpsa.journals.ekb.eg/service?article_code=102092

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6

Type

Original Article

Type Code

1,096

Publication Type

Journal

Publication Title

Bulletin of Pharmaceutical Sciences Assiut University

Publication Link

https://bpsa.journals.ekb.eg/

MainTitle

EFFECT OF PH, TEMPERATURE AND CERTAIN ADDITIVES ON THE SOLUBILIZATION OF CARBAMAZEPINE BY SELECTED NON-IONIC SURFACTANT SOLUTIONS

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Article

Created At

22 Jan 2023