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89873

WITHANOLIDES OF WITHANIA SOMNIFERA L. DUNAL GROWING WILD IN EGYPT

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Last updated: 04 Jan 2025

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Abstract

 Three Withanolides (Substances A,B, and C) were isolated from the alcoholic extract of the Egyptian Withania somnifera wild plants. Substance A and substance C were identified by IR, NMR and Mass spectral data. Substance A appears to be a configurational isomer of Withanolide E and substance C is 4-hydroxy derivative of substance A. Substance A is identified as 14,17,20-trihydroxy-5B,6B-epoxy-1-oxo-Witha-2,24-dienolide (I) and substance C as 4,14,17,20-tetrahydroxy-5B, 6B-epoxy-1-oxo-witha-2,24-dienolide(II). This is the first report of isolation and characterization of substance C from Withania somnifera or the genus Withania. Substance B would be the subject of a further report.

DOI

10.21608/bfsa.1984.89873

Authors

First Name

M.

Last Name

El-Olemy

MiddleName

M.

Affiliation

Department of Pharmacognosy, Faculty of Pharmacy, Tanta University, Tanta, Egypt

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City

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Orcid

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First Name

H.

Last Name

Kadry

MiddleName

A.

Affiliation

Department of Pharmacognosy, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt

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Volume

7

Article Issue

2

Related Issue

13482

Issue Date

1984-12-01

Receive Date

1984-07-14

Publish Date

1984-12-31

Page Start

430

Page End

443

Print ISSN

1110-0052

Online ISSN

3009-7703

Article File

BFSA_Volume 7_Issue 2_Pages 430-443.pdf

PDF . 485.9kB

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https://bpsa.journals.ekb.eg/article_89873.html

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https://bpsa.journals.ekb.eg/service?article_code=89873

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Original Article

Type Code

1,096

Publication Type

Journal

Publication Title

Bulletin of Pharmaceutical Sciences Assiut University

Publication Link

https://bpsa.journals.ekb.eg/

MainTitle

WITHANOLIDES OF WITHANIA SOMNIFERA L. DUNAL GROWING WILD IN EGYPT

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Article

Created At

22 Jan 2023