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89707

ENHANCED DISSOLUTION RATE OF IBUPROFEN USING SURFACTANTS AND WATER SOLUBLE CARRIERS

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Last updated: 25 Dec 2024

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Abstract

The influence of some non-ionic surfactants as well as polyethylene glycol 6000 and dextrose as water soluble carrier, on the dissolution of poorly soluble drug, ibuprofen, was studied. Surfactants produced better drug release than the polyethylene glycol and dextrose with the drug carrier ratio studied. TLC and IR studied ruled out any interaction between the drug and any of the additives used. In addition, the bulkness of the drug was not affected by the amount of surfactants added, as being found with dextrose and polyethylene glycol 6000.

DOI

10.21608/bfsa.1984.89707

Authors

First Name

M.

Last Name

El-Shaboury

MiddleName

-

Affiliation

Department of Pharmaceutics, Facutly of Pharmacy, Mansoura University, Mansoura, Egypt

Email

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Orcid

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First Name

A.

Last Name

Nouh

MiddleName

T.

Affiliation

Department of Pharmaceutics, Facutly of Pharmacy, Mansoura University, Mansoura, Egypt

Email

-

City

-

Orcid

-

First Name

A.

Last Name

Abd El-Gawad

MiddleName

H.

Affiliation

Department of Pharmaceutics, Facutly of Pharmacy, Mansoura University, Mansoura, Egypt

Email

-

City

-

Orcid

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Volume

7

Article Issue

2

Related Issue

13482

Issue Date

1984-12-01

Receive Date

1983-11-24

Publish Date

1984-12-31

Page Start

295

Page End

304

Print ISSN

1110-0052

Online ISSN

3009-7703

Article File

BFSA_Volume 7_Issue 2_Pages 295-304.pdf

PDF . 318.9kB

Link

https://bpsa.journals.ekb.eg/article_89707.html

Detail API

https://bpsa.journals.ekb.eg/service?article_code=89707

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Type

Original Article

Type Code

1,096

Publication Type

Journal

Publication Title

Bulletin of Pharmaceutical Sciences Assiut University

Publication Link

https://bpsa.journals.ekb.eg/

MainTitle

ENHANCED DISSOLUTION RATE OF IBUPROFEN USING SURFACTANTS AND WATER SOLUBLE CARRIERS

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Article

Created At

22 Jan 2023