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89688

FORMULATION AND STABILITY OF HEPTAMINOL DROPS

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Last updated: 04 Jan 2025

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Abstract

Several aqueous solvents were tried for the formulation of Heptaminol base in oral drops. Also, some stabilizing agents were evaluated for their action on the stability of Heptaminol base in the selected solvents. It was observed that distilled water conferred the best stability to Heptaminol base even when compared to market drope. Inclusion of 0.1 percent sodium thiosulphate in the latter solvent seems to be ineffective for further stabilization. In other solvents, the antioxidants tried largely detracted from the stability of Heptaminol base. In addition, 50 percent sorbitol in water was clearly found the worst solvent with regards to Heptaminol stability.

DOI

10.21608/bfsa.1984.89688

Authors

First Name

Ali

Last Name

Kassem

MiddleName

A.

Affiliation

Department of Pharmaceutics, Faculty of Pharmacy, Cairo University, Cairo, Egypt

Email

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Orcid

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First Name

Mohamed

Last Name

El-Miligi

MiddleName

F.

Affiliation

Department of Pharmaceutics, Faculty of Pharmacy, Cairo University, Cairo, Egypt

Email

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City

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Orcid

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First Name

Siham

Last Name

Ali

MiddleName

A.

Affiliation

Department of Pharmaceutics, Faculty of Pharmacy, Cairo University, Cairo, Egypt

Email

-

City

-

Orcid

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Volume

7

Article Issue

2

Related Issue

13482

Issue Date

1984-12-01

Receive Date

1983-02-10

Publish Date

1984-12-31

Page Start

251

Page End

260

Print ISSN

1110-0052

Online ISSN

3009-7703

Article File

BFSA_Volume 7_Issue 2_Pages 251-260.pdf

PDF . 334.9kB

Link

https://bpsa.journals.ekb.eg/article_89688.html

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https://bpsa.journals.ekb.eg/service?article_code=89688

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Original Article

Type Code

1,096

Publication Type

Journal

Publication Title

Bulletin of Pharmaceutical Sciences Assiut University

Publication Link

https://bpsa.journals.ekb.eg/

MainTitle

FORMULATION AND STABILITY OF HEPTAMINOL DROPS

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Article

Created At

22 Jan 2023