Beta
ManageSearchChatDiscover
74588

PREFORMULATION STUDIES ON DIRECTLY COMPRESSED TEMAZEPAM TABLETS

Article

Last updated: 25 Dec 2024

OverviewSimilar Items

Subjects

-

Tags

-

Abstract

Temazepam, a benzodiazepine derivative, was prepared in directly compressed tablets using Avicel, Anhydrous Lactose (A.H.L.), STA-Rx 1500, Emcompress and Compactrol. It was found that A.H.L. represents the most suitable single vehicle while Avicel : STA-RX 1:1 blend was the most suitable blend for the preparation of temazepam tablets. STA-RX 1500 and its blends with the other used vehicles were shown to give the highest dissolution. The most uniform tablets were produced on using Emcompress alone or as a binary blend with Avicel (1:1) as directly compressible vehicles.

DOI

10.21608/bfsa.1986.74588

Authors

First Name

A.

Last Name

Aboutaleb

MiddleName

E.

Affiliation

Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt

Email

-

City

-

Orcid

-

First Name

A.

Last Name

Abdel Rahman

MiddleName

A.

Affiliation

Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt

Email

-

City

-

Orcid

-

First Name

M.

Last Name

Ahmed

MiddleName

O.

Affiliation

Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt

Email

-

City

-

Orcid

-

Volume

9

Article Issue

2

Related Issue

11260

Issue Date

1986-12-01

Receive Date

1986-10-20

Publish Date

1986-12-31

Page Start

172

Page End

186

Print ISSN

1110-0052

Online ISSN

3009-7703

Article File

BFSA_Volume 9_Issue 2_Pages 172-186.pdf

PDF . 422.6kB

Link

https://bpsa.journals.ekb.eg/article_74588.html

Detail API

https://bpsa.journals.ekb.eg/service?article_code=74588

Order

12

Type

Original Article

Type Code

1,096

Publication Type

Journal

Publication Title

Bulletin of Pharmaceutical Sciences Assiut University

Publication Link

https://bpsa.journals.ekb.eg/

MainTitle

PREFORMULATION STUDIES ON DIRECTLY COMPRESSED TEMAZEPAM TABLETS

Details

Type

Article

Created At

22 Jan 2023