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74582

SYNTHESIS OF SOME 2,7-DIAZABICYCLO {4.l.0} HEPT-3-ENE DERIVATIVES WITH ANALGESIC AND ANTICOCCIDIAL ACTIVITY

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Last updated: 25 Dec 2024

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Abstract

The 1,3-dipolar cycloaddition reaction of arylsulphonyl azides to 1,3-disubstituted-1,4-dihydropyridines afforded 2,7-diazabieyclo {4.1.0} hept-3-ene derivatives (III).These compounds exhibited more significant analgesic and anticoccidial activities than aspirin and sulphaguanidine respectively.

DOI

10.21608/bfsa.1986.74582

Authors

First Name

H.

Last Name

Farag

MiddleName

H.

Affiliation

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt

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City

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Orcid

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First Name

A.

Last Name

Abdel-Alim

MiddleName

M.

Affiliation

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt

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City

-

Orcid

-

First Name

H.

Last Name

Hassan

MiddleName

Y.

Affiliation

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt

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Orcid

-

First Name

H.

Last Name

Hemaiat-Allah

MiddleName

A.

Affiliation

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt

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Orcid

-

First Name

R.

Last Name

Abdel-Aal

MiddleName

A.

Affiliation

Department of Pharmacology, Faculty of Medicine, Assiut University, Assiut, Egypt

Email

-

City

-

Orcid

-

First Name

A.

Last Name

El-Badr

MiddleName

M.

Affiliation

Department of Parasitology, Faculty of Medicine, Assiut University, Assiut, Egypt

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Volume

9

Article Issue

2

Related Issue

11260

Issue Date

1986-12-01

Receive Date

1986-09-02

Publish Date

1986-12-31

Page Start

105

Page End

118

Print ISSN

1110-0052

Online ISSN

3009-7703

Article File

BFSA_Volume 9_Issue 2_Pages 105-118.pdf

PDF . 357.0kB

Link

https://bpsa.journals.ekb.eg/article_74582.html

Detail API

https://bpsa.journals.ekb.eg/service?article_code=74582

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8

Type

Original Article

Type Code

1,096

Publication Type

Journal

Publication Title

Bulletin of Pharmaceutical Sciences Assiut University

Publication Link

https://bpsa.journals.ekb.eg/

MainTitle

SYNTHESIS OF SOME 2,7-DIAZABICYCLO {4.l.0} HEPT-3-ENE DERIVATIVES WITH ANALGESIC AND ANTICOCCIDIAL ACTIVITY

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Article

Created At

22 Jan 2023