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74575

SYNTHESIS AND ANTIBACTERIAL TESTING OF SOME NEW SELENADIAZOLE AND THIADIAZOLE CONTAINING AMINO ACID MOIETIES

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Last updated: 04 Jan 2025

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Abstract

Several 4-{4-(substitutedglycylamino)-phenyl}-1,2,3-selenadiazols (IV) and 4{4-(substitutedglycylamino)phenyl}-1,2,3-thiadiazoles (V) were prepared for evaluation of their antimicrobial activity. 4-chloroacetylaminoacetophenone (I) when reacted with different amines gave 4-glycylaminoacetophenone derivatives (II), Condensation of II with semicarbazide furnished the corresponding semicrabazones (III). Oxidative cyclization of (III) either by selenium dioxide or thionyl chloride afforded IV and V respectively.

DOI

10.21608/bfsa.1986.74575

Authors

First Name

B.

Last Name

Bayoumi

MiddleName

E.

Affiliation

Department of Chemistry, Faculty of Science, Zagazig University, Zagazig, Egypt

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Orcid

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First Name

M.

Last Name

Abd-Alla

MiddleName

A.

Affiliation

Department of Chemistry, Faculty of Science, Assiut University, Assiut, Egypt

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City

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Orcid

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First Name

A.

Last Name

Ahmed

MiddleName

N.

Affiliation

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt

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Volume

9

Article Issue

2

Related Issue

11260

Issue Date

1986-12-01

Receive Date

1986-06-03

Publish Date

1986-12-31

Page Start

66

Page End

77

Print ISSN

1110-0052

Online ISSN

3009-7703

Article File

BFSA_Volume 9_Issue 2_Pages 66-77.pdf

PDF . 347.2kB

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https://bpsa.journals.ekb.eg/article_74575.html

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https://bpsa.journals.ekb.eg/service?article_code=74575

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Original Article

Type Code

1,096

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Journal

Publication Title

Bulletin of Pharmaceutical Sciences Assiut University

Publication Link

https://bpsa.journals.ekb.eg/

MainTitle

SYNTHESIS AND ANTIBACTERIAL TESTING OF SOME NEW SELENADIAZOLE AND THIADIAZOLE CONTAINING AMINO ACID MOIETIES

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Article

Created At

22 Jan 2023