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74483

UTILITY OF XANTHYDROL FOR THE SPECTROPHOTOMETRIC DETERMINATION OF CERTAIN PHARMACEUTICAL PHENOLS

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Last updated: 04 Jan 2025

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Abstract

The reaction of xanthydrol with phenols was applied for the determination of thymol, guaiacol, morin and naringenin, out of 30 phenolic compounds tested. Mixture of methanolic solutions of the phenol and xanthydrol was heated in presence of hydrochloric acid for 10 minutes on a water bath. The lmax of the coloured chromogen was located in the vicinity of 485 nm (orange) to 540 nm (violet). Molar absorptivities range from 1.0x103 to 4.3x103. A linear correlation was found between absorbance at lmax and concentration in the range of 5-40 mcg ml-1 (for thymol), 20-100 mcg ml-1 (for guaiacol) and 20-150 mcg ml-1 (for morin and naringenin).

DOI

10.21608/bfsa.1986.74483

Authors

First Name

Michael

Last Name

El-Kommos

MiddleName

E.

Affiliation

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt

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Volume

9

Article Issue

2

Related Issue

11260

Issue Date

1986-12-01

Receive Date

1986-04-28

Publish Date

1986-12-31

Page Start

1

Page End

13

Print ISSN

1110-0052

Online ISSN

3009-7703

Article File

BFSA_Volume 9_Issue 2_Pages 1-13.pdf

PDF . 305.7kB

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https://bpsa.journals.ekb.eg/article_74483.html

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https://bpsa.journals.ekb.eg/service?article_code=74483

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Original Article

Type Code

1,096

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Journal

Publication Title

Bulletin of Pharmaceutical Sciences Assiut University

Publication Link

https://bpsa.journals.ekb.eg/

MainTitle

UTILITY OF XANTHYDROL FOR THE SPECTROPHOTOMETRIC DETERMINATION OF CERTAIN PHARMACEUTICAL PHENOLS

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Article

Created At

22 Jan 2023