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74470

ADSORPTION OF ROTOXAMINE TARTRATE BY AVICEL pH 101

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Last updated: 25 Dec 2024

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Abstract

The adsorption of rotoxamine tartrate (RT) by avicel pH 101 was studied at a variety of pH values and in the presence of different concentrations of sodium lauryl sulfate (SLS), sodium cholate (SC), PVP 44000 and different electrolytic species. The results obtained were well described by the Langmuir equation. The limiting adsorptive capacity and the affinity constant were calculated. The data revealed that as the pH value was increased the limiting adsorptive capacity (a value) decreased. The results also revealed that as the concentration of SLS or SC was increased the affinity of the drug to be adsorbed was decreased. The adsorption of RT was found to be dependent on the type of the electrolyte used. It was found that the degree of adsorption decreased as the valence of the basic radicle of the elyctrolyte increased. PVP was found to have a suppression effect on the amount of RT adsorbed by avicel. Interpretation of the results obtained is also offered.

DOI

10.21608/bfsa.1986.74470

Authors

First Name

Sayed

Last Name

Ismail

MiddleName

-

Affiliation

Department of Pharmaceutics, Faculty of Pharmacy, Assiut University, Assiut Egypt

Email

sayed.hussien@pharm.aun.edu.eg

City

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Orcid

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First Name

Sohair

Last Name

El-Shanawany

MiddleName

-

Affiliation

Department of Pharmaceutics, Faculty of Pharmacy, Assiut University, Assiut Egypt

Email

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City

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Orcid

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Volume

9

Article Issue

1

Related Issue

11257

Issue Date

1986-06-01

Receive Date

1986-01-08

Publish Date

1986-06-30

Page Start

11

Page End

24

Print ISSN

1110-0052

Online ISSN

3009-7703

Article File

BFSA_Volume 9_Issue 1_Pages 11-24.pdf

PDF . 366.2kB

Link

https://bpsa.journals.ekb.eg/article_74470.html

Detail API

https://bpsa.journals.ekb.eg/service?article_code=74470

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Type

Original Article

Type Code

1,096

Publication Type

Journal

Publication Title

Bulletin of Pharmaceutical Sciences Assiut University

Publication Link

https://bpsa.journals.ekb.eg/

MainTitle

ADSORPTION OF ROTOXAMINE TARTRATE BY AVICEL pH 101

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Article

Created At

22 Jan 2023