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70565

FORMULATION AND EVALUATION OF BENZOYL METRONIDAZOLE SUSPENSION

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Last updated: 25 Dec 2024

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Abstract

Two formulae of benzoyl metronidazole suspension were prepared. One consisted of Tween 40 (0.2%), sodium carboxymethyl cellulose (1%), and potassium dihydrogen phosphate (0.002%) [formula No. 1] and sodium chloride (.005%) instead of potassium, dihydrogen phosphate (formula No. 2]. The formulated suspensions, were found to be superior than the commercial one. The sediment was one layer compared to two layers sediment of the commercial product. The supernatants were clear and the suspensions were easily re-dispersed. The percent drug dissoluted was higher than that of the commercial product. The prepared suspensions showed physical and chemical stabi1ity even after 12 months of aging.

DOI

10.21608/bfsa.1990.70565

Authors

First Name

S.

Last Name

Ibrahim

MiddleName

A.

Affiliation

Department of Pharmaceutics, Faculty of Pharmacy, Assiut University, Assiut, Egypt

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Orcid

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First Name

S.

Last Name

Tous

MiddleName

Shawky

Affiliation

Department of Pharmaceutics, Faculty of Pharmacy, Assiut University, Assiut, Egypt

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Orcid

-

First Name

T.

Last Name

El-Faham

MiddleName

H.

Affiliation

Department of Pharmaceutics, Faculty of Pharmacy, Assiut University, Assiut, Egypt

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City

-

Orcid

-

First Name

M.

Last Name

Hassan

MiddleName

H.

Affiliation

Department of Pharmaceutics, Faculty of Pharmacy, Assiut University, Assiut, Egypt

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Volume

13

Article Issue

2

Related Issue

10752

Issue Date

1990-12-01

Receive Date

1990-12-08

Publish Date

1990-12-31

Page Start

169

Page End

180

Print ISSN

1110-0052

Online ISSN

3009-7703

Article File

BFSA_Volume 13_Issue 2_Pages 169-180.pdf

PDF . 493.6kB

Link

https://bpsa.journals.ekb.eg/article_70565.html

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https://bpsa.journals.ekb.eg/service?article_code=70565

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Original Article

Type Code

1,096

Publication Type

Journal

Publication Title

Bulletin of Pharmaceutical Sciences Assiut University

Publication Link

https://bpsa.journals.ekb.eg/

MainTitle

FORMULATION AND EVALUATION OF BENZOYL METRONIDAZOLE SUSPENSION

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Article

Created At

22 Jan 2023