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70216

EVALUATION OF TABLETED CINNARIZINE-MICROCRYSTALLINE CELLULOSE GROUND MIXTURE

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Last updated: 25 Dec 2024

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Abstract

Fast release cinnarizine (CN) tablets were prepared by the direct compression of CN-microcrytalline cellulose (1:3) ground mixture. Directly compressed tablets containing either untreated CN or ground CN were also prepared for comparison. Avicel PH 101 was used as the direct compression excipient in each case. The produced tablets were evaluated with regard to their dissolution characteristics, their drug content uniformity and their physical properties including uniformity of weight, hardness, friability and disintegration time. Tablets compressed containing CN-microcrystalline cellulose ground mixture showed good physical properties, better drug content uniformity and superior dissolution characteristics compared to the tablets containing untreated or ground alone CN.

DOI

10.21608/bfsa.1992.70216

Authors

First Name

S.

Last Name

Ahmed

MiddleName

M.

Affiliation

Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt

Email

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City

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Orcid

-

First Name

S.

Last Name

Saleh

MiddleName

I.

Affiliation

Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt

Email

-

City

-

Orcid

-

First Name

A.

Last Name

Aboutaleb

MiddleName

E.

Affiliation

Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt

Email

-

City

-

Orcid

-

Volume

15

Article Issue

1

Related Issue

10665

Issue Date

1992-12-01

Receive Date

1991-11-23

Publish Date

1992-12-31

Page Start

57

Page End

62

Print ISSN

1110-0052

Online ISSN

3009-7703

Article File

BFSA_Volume 15_Issue 1_Pages 57-62.pdf

PDF . 286.0kB

Link

https://bpsa.journals.ekb.eg/article_70216.html

Detail API

https://bpsa.journals.ekb.eg/service?article_code=70216

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Type

Original Article

Type Code

1,096

Publication Type

Journal

Publication Title

Bulletin of Pharmaceutical Sciences Assiut University

Publication Link

https://bpsa.journals.ekb.eg/

MainTitle

EVALUATION OF TABLETED CINNARIZINE-MICROCRYSTALLINE CELLULOSE GROUND MIXTURE

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Article

Created At

22 Jan 2023