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70205

IMPROVED DELIVERY THROUGH BIOLOGICAL MEMBRANES: PREPARATION AND INVESTIGATION OF STABLE DOPAMINE CHEMICAL DELIVERY SYSTEM SAMPLES

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Last updated: 25 Dec 2024

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Abstract

 Crystalline dopamine chemical delivery system and its cyclodextrin complex could be prepared. The crystalline compound showed better stability at different storage conditions. The iv injection of aqueous solutions of the complex showed higher brain delivery than the DMSO solution of the pure compound. The ip Injection of the aqueous solution of the complex delivered good concentration of the deacylated dopamine quaternary (dopamine prodrug-moiety) to the brain.

DOI

10.21608/bfsa.1993.70205

Authors

First Name

Nicholas

Last Name

Bodor

MiddleName

-

Affiliation

Center for Drug Discovery, College of Pharmacy, J. Hillis Miller Health Center, University of Florida, Gainesville, Florida 32610

Email

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City

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Orcid

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First Name

Hassan

Last Name

Farag

MiddleName

H.

Affiliation

Department of Medicinal Pharmaceutical Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt

Email

-

City

-

Orcid

-

First Name

Farghaly

Last Name

Omar

MiddleName

A.

Affiliation

Department of Medicinal Pharmaceutical Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt

Email

-

City

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Orcid

-

Volume

16

Article Issue

2

Related Issue

10642

Issue Date

1993-12-01

Receive Date

1993-08-01

Publish Date

1993-12-31

Page Start

175

Page End

182

Print ISSN

1110-0052

Online ISSN

3009-7703

Article File

BFSA_Volume 16_Issue 2_Pages 175-182.pdf

PDF . 531.8kB

Link

https://bpsa.journals.ekb.eg/article_70205.html

Detail API

https://bpsa.journals.ekb.eg/service?article_code=70205

Order

9

Type

Original Article

Type Code

1,096

Publication Type

Journal

Publication Title

Bulletin of Pharmaceutical Sciences Assiut University

Publication Link

https://bpsa.journals.ekb.eg/

MainTitle

IMPROVED DELIVERY THROUGH BIOLOGICAL MEMBRANES: PREPARATION AND INVESTIGATION OF STABLE DOPAMINE CHEMICAL DELIVERY SYSTEM SAMPLES

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Article

Created At

22 Jan 2023