Beta
ManageSearchChatDiscover
70030

SUSTAINED RELEASE FORMULATIONS OF PHENAZOPYRIDINE HYDROCHLORIDE WITH CELLULOSE ACETATE PHTHALATE

Article

Last updated: 25 Dec 2024

OverviewSimilar Items

Subjects

-

Tags

-

Abstract

Cellulose acetate phthalate (CAP) was utilized for the preparation of sustained release formulations of phenazopyridine hydrochloride (PHCl) by three different techniques: (a) solid dispersion (coprecipitation), (b) microencapsulation. by phase separation coacervation using non-solvent addition technique and (c) pan coating. The three techniques studied resulted in different extents of sustaining the release of PHCl, in vitro, compared to the untreated drug. Pan coating proved to be the easiest and most convenient: technique for the preparation of sustained release PHCl microcapsules. With regard to the release kinetics of PHCl from each of the formulations prepared, the first order model was found to be the most suitable mechanism describing the release of the drug.

DOI

10.21608/bfsa.1993.70030

Authors

First Name

A.

Last Name

Aly

MiddleName

M.

Affiliation

Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt

Email

-

City

-

Orcid

-

First Name

S.

Last Name

Ahmed

MiddleName

M.

Affiliation

Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt

Email

-

City

-

Orcid

-

First Name

S.

Last Name

Abdel-Rahman

MiddleName

I.

Affiliation

Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt

Email

-

City

-

Orcid

-

First Name

S.

Last Name

Saleh

MiddleName

I.

Affiliation

Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt

Email

-

City

-

Orcid

-

First Name

A.

Last Name

Aboutaleb

MiddleName

E.

Affiliation

Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt

Email

-

City

-

Orcid

-

Volume

16

Article Issue

1

Related Issue

10639

Issue Date

1993-06-01

Receive Date

1992-12-13

Publish Date

1993-06-30

Page Start

63

Page End

72

Print ISSN

1110-0052

Online ISSN

3009-7703

Article File

BFSA_Volume 16_Issue 1_Pages 63-72.pdf

PDF . 436.3kB

Link

https://bpsa.journals.ekb.eg/article_70030.html

Detail API

https://bpsa.journals.ekb.eg/service?article_code=70030

Order

7

Type

Original Article

Type Code

1,096

Publication Type

Journal

Publication Title

Bulletin of Pharmaceutical Sciences Assiut University

Publication Link

https://bpsa.journals.ekb.eg/

MainTitle

SUSTAINED RELEASE FORMULATIONS OF PHENAZOPYRIDINE HYDROCHLORIDE WITH CELLULOSE ACETATE PHTHALATE

Details

Type

Article

Created At

22 Jan 2023