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69788

TEMAZEPAM--CYCLODEXTRIN AND TEMAZEPAM-MICROCRYSTALLINE CELLULOSE GROUND MIXTURES FORMULATED INTO TABLETS, CAPSULES AND SUPPOSITORIES

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Last updated: 25 Dec 2024

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Abstract

Temazepam-b-cyclodextrin and temazepam-microcrystalline cellulose ground mixtures were formulated into tablets, capsules and suppositories. The produced dosage forms were evaluated with regard to their physical properties and dissolution characteristic. Tablets containing temazepam-b-cyclodextrin or temazepam-microcrystalline cellulose ground mixtures showed reasonable physical properties andfaster dissolution characteristics compared to those containing untreated temazepam or ground alone one. Capsules containing Temazepam-b-cyclodextrin or temazepam-microcrystalline cellulose ground mixtures 'showed faster release characteristics compared to those containing untreated temazepam, the ground alone one or the. commercial temazepam capsule form studied. With regard to the-prepared suppositories, Witepsole H 15 gave rise to suppositories with a very slow release whereas, a mixture of PEG 1500 and PEG 400 (9:1 W/W) gave rise to suppositories with very fast release characteristics.

DOI

10.21608/bfsa.1994.69788

Authors

First Name

S.

Last Name

Saleh

MiddleName

I.

Affiliation

Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt

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Orcid

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First Name

S.

Last Name

Ahmed

MiddleName

M.

Affiliation

Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt

Email

-

City

-

Orcid

-

First Name

M.

Last Name

Ahmed

MiddleName

O.

Affiliation

Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt

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-

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-

Orcid

-

Volume

17

Article Issue

1

Related Issue

10608

Issue Date

1994-07-01

Receive Date

1994-01-27

Publish Date

1994-07-31

Page Start

57

Page End

64

Print ISSN

1110-0052

Online ISSN

3009-7703

Article File

BFSA_Volume 17_Issue 1_Pages 57-64.pdf

PDF . 446.3kB

Link

https://bpsa.journals.ekb.eg/article_69788.html

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https://bpsa.journals.ekb.eg/service?article_code=69788

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Original Article

Type Code

1,096

Publication Type

Journal

Publication Title

Bulletin of Pharmaceutical Sciences Assiut University

Publication Link

https://bpsa.journals.ekb.eg/

MainTitle

TEMAZEPAM--CYCLODEXTRIN AND TEMAZEPAM-MICROCRYSTALLINE CELLULOSE GROUND MIXTURES FORMULATED INTO TABLETS, CAPSULES AND SUPPOSITORIES

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Article

Created At

22 Jan 2023