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69684

3-(ETHOXYCARBONYL)-2-METHYLPYRROLE-5-CARBOXALDEHYDE AS A VERSATILE SYNTHONE FOR POTENTIAL ANTIBACTERIAL AGENTS

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Last updated: 25 Dec 2024

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Abstract

Reaction of 3-(ethoxycarbonyl)-2-methylpyrrole-5-carboxaldehyde with substituted thiosemicarbazides afforded the corresponding (thiocarbamoyl) hydrazones. The latter compounds underwent cyclization to thiazole, thiazolidinone, thiazinone and thiadizole derivatives under the proper reaction condition. All the prepared compounds were evaluated for this antimicrobial activity.

DOI

10.21608/bfsa.1995.69684

Authors

First Name

Hassan

Last Name

Mokhtar

MiddleName

M.

Affiliation

Department of Chemistry, Faculty of Science, Alexandria University, Alexandria, Egypt

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Orcid

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First Name

Ola

Last Name

El-Sayed

MiddleName

A.

Affiliation

Department of Botany and Microbiology, Faculty of Science, Alexandria University, Alexandria, Egypt

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City

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Orcid

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First Name

Azza

Last Name

El-Sabaeny

MiddleName

H.

Affiliation

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt

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Volume

18

Article Issue

2

Related Issue

10588

Issue Date

1995-12-01

Receive Date

1995-04-17

Publish Date

1995-12-31

Page Start

59

Page End

67

Print ISSN

1110-0052

Online ISSN

3009-7703

Link

https://bpsa.journals.ekb.eg/article_69684.html

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https://bpsa.journals.ekb.eg/service?article_code=69684

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Original Article

Type Code

1,096

Publication Type

Journal

Publication Title

Bulletin of Pharmaceutical Sciences Assiut University

Publication Link

https://bpsa.journals.ekb.eg/

MainTitle

3-(ETHOXYCARBONYL)-2-METHYLPYRROLE-5-CARBOXALDEHYDE AS A VERSATILE SYNTHONE FOR POTENTIAL ANTIBACTERIAL AGENTS

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Article

Created At

22 Jan 2023