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68754

MOLLUSCICIDAL SPIROSTANOL SAPONINS FROM AGAVE HETERACANTHA

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Last updated: 04 Jan 2025

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Abstract

Four spirostanol saponin glycosides were isolated from the butanol fraction of the methanolic extract of the leaves of Agave heteracantha (Agavaceae). The structures of these saponins were elucidated by a combination of spectroscopic analysis and hydrolysis followed by identification of both aglycones as tigogenin and gitogenin as well as the sugar moieties. The four saponins exhibited strong molluscicidal activites against Biomphalaria alexandrina (LC90 = 10, 15, 7 and 9 ppm) and Lymnaea cailliaudi (LC90 = 8, 13, 5 and 6 ppm), the intermediate hosts of Schistosoma mansoni and Fasciola gigantica in Egypt respectively.

DOI

10.21608/bfsa.1997.68754

Authors

First Name

Mortada

Last Name

El-Sayed

MiddleName

M.

Affiliation

Laboratory of Medicinal Chemistry, Theodor Bilharz Research Institute, Imbaba, Giza, Egypt

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Volume

20

Article Issue

2

Related Issue

10408

Issue Date

1997-12-01

Receive Date

1997-05-22

Publish Date

1997-12-31

Page Start

147

Page End

153

Print ISSN

1110-0052

Online ISSN

3009-7703

Article File

BFSA_Volume 20_Issue 2_Pages 147-153.pdf

PDF . 482.6kB

Link

https://bpsa.journals.ekb.eg/article_68754.html

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https://bpsa.journals.ekb.eg/service?article_code=68754

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Original Article

Type Code

1,096

Publication Type

Journal

Publication Title

Bulletin of Pharmaceutical Sciences Assiut University

Publication Link

https://bpsa.journals.ekb.eg/

MainTitle

MOLLUSCICIDAL SPIROSTANOL SAPONINS FROM AGAVE HETERACANTHA

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Article

Created At

22 Jan 2023