From the chloroform ext. of the aerial parts of Tanacetum santolinoides (DC.)​, four methoxylated flavonoids were isolated.  Characterization and structure elucidation were conducted through spectral data (¹H-​NMR, ¹³C-​NMR, ¹H, ¹H-​COSY, ¹H, ¹³C-​COSY, HMBC and MS expts.)​.  The isolated flavonoids were identified as artemetin, jaceosidin, chrysoeriol and diosmetin.  More over stigmasterol 3-​O-​β-​D-​glucoside was also isolated and identified.  This is the first report for the isolation of these compds. from the title plant.