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65703

Phytochemical and biological studies on the leaves of Tecoma mollis Humb. And Bonpl cultivated in Egypt

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Last updated: 25 Dec 2024

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Abstract

α-​Amyrin, 3-​β-​hydroxy-​urs-​12-​ene-​28-​aldehyde, β-​sitosterol, ursolic acid lactone, ursolic acid, 2-​β,​3-​,​β,​19-​α-​trihydroxy-​urs-​12-​ene-​28-​oic acid (2-​tormentic acid)​, β-​sitosterol-​3-​O-​β-​D-​glucoside, apigenin-​7-​O-​α-​L-​rhamnoside, apigenin-​7-​O-​rutinoside, luteolin-​7-​O-​rutinoside, and apigenin-​6,​8-​di-​C-​β-​D-​glucopyranoside (vicenin 2) (11) were isolated for the first time fron an ethanolic ext. of the leaves of Tecoma mollis Humb and Bonpl. cultivated in Egypt.  Identification of these compds. has been established by phys. and spectral data (UV, IR, MS, 1H- and 13C-​NMR) as well as by comparison with authentic samples.  Moreover, the biol. screening showed that the non polar fraction of the alc. ext. (n-​hexane, chloroform)​, polar fraction (Et acetate, n-​butanol) and aq. ext. as well as ursolic acid possess significant anti-​inflammatory, analgesic and antipyretic activities.  In addn., the polar fraction and aq. ext. possess also a significant anticonvulsant activity.

DOI

10.21608/bfsa.2002.65703

Authors

First Name

Nasr

Last Name

El-Emary

MiddleName

A.

Affiliation

Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt

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Orcid

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First Name

Azza

Last Name

Khalifa

MiddleName

A.

Affiliation

Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt

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City

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Orcid

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First Name

Enaam

Last Name

Backheet

MiddleName

Y.

Affiliation

Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt

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City

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Orcid

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First Name

Wael

Last Name

Abdel-Mageed

MiddleName

M.

Affiliation

Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt

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Orcid

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Volume

25

Article Issue

2

Related Issue

9910

Issue Date

2002-12-01

Receive Date

2002-09-23

Publish Date

2002-12-31

Page Start

297

Page End

228

Print ISSN

1110-0052

Online ISSN

3009-7703

Link

https://bpsa.journals.ekb.eg/article_65703.html

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https://bpsa.journals.ekb.eg/service?article_code=65703

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Original Article

Type Code

1,096

Publication Type

Journal

Publication Title

Bulletin of Pharmaceutical Sciences Assiut University

Publication Link

https://bpsa.journals.ekb.eg/

MainTitle

Phytochemical and biological studies on the leaves of Tecoma mollis Humb. And Bonpl cultivated in Egypt

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Article

Created At

22 Jan 2023