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156605

PHYTOCHEMICAL AND BIOLOGICAL STUDIES ON THE LEAVES OF TECOMA MOLLIS HUMB. AND BONPL CULTIVATED IN EGYPT

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Last updated: 25 Dec 2024

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Abstract

a-Amyrin (1), 3-b-hydroxy-urs-12-ene-28-aldehyde (2) b-sitosterol (3), ursolic acid lactone (4), ursolic acid (5), 2-b,3-b,19-a-trihydroxy-urs-12-ene-28-oic acid (2-tormentic acid) (6), b-sitosterol-3-O-b-D-glucoside (7) apigenin-7-O-a-L-rhamnoside (8), apigenin-7-O-rutinoside (9), luteolin-7-O-rutinoside (10) and apigenin-6,8-di-C-b-D-glucopyranoside (Vicenin 2) (11) were isolated for the first time from the ethanolic extract of the leaves of Tecoma mollis Humb and Bonpl. cultivated in Egypt. Identification of these compounds has been established by physical and spectral data (UV, IR, MS, 1H- and 13C-NMR) as well as by comparison with authentic samples. Moreover, the biological screening showed that the non-polar fraction of the alcoholic extract (n-hexane, chloroform), polar fraction (ethyl acetate, n-butanol) and aqueous extract as well as ursolic acid possess significant anti-inflammatory, analgesic and antipyretic activities. In addition, the polar fraction and aqueous extract possess also a significant anticonvulsant activity.

DOI

10.21608/bfsa.2002.156605

Authors

First Name

Nasr

Last Name

A. El-Emary

MiddleName

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Affiliation

Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt

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First Name

Azza

Last Name

A. Khalifa

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Affiliation

Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt

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Orcid

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First Name

Enaam

Last Name

Y. Backheet

MiddleName

-

Affiliation

Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt

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Orcid

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First Name

Wael

Last Name

M. Abdel-Mageed

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Affiliation

Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt

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Volume

25

Article Issue

2

Related Issue

9910

Issue Date

2002-12-01

Receive Date

2002-09-23

Publish Date

2002-12-31

Page Start

207

Page End

228

Print ISSN

1110-0052

Online ISSN

3009-7703

Link

https://bpsa.journals.ekb.eg/article_156605.html

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https://bpsa.journals.ekb.eg/service?article_code=156605

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Original Article

Type Code

1,096

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Journal

Publication Title

Bulletin of Pharmaceutical Sciences Assiut University

Publication Link

https://bpsa.journals.ekb.eg/

MainTitle

PHYTOCHEMICAL AND BIOLOGICAL STUDIES ON THE LEAVES OF TECOMA MOLLIS HUMB. AND BONPL CULTIVATED IN EGYPT

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Article

Created At

22 Jan 2023