Quality control study was carried out using three pharmaceutical preparations namely, ispaghula Husk (Fypogel), senna (Senokot) and chamomile (Bonomelli) which were selected from Libyan market. This study was carried out to insure their safety and efficacy through determination of their physical, chemical and microbiological characters. The obtained data were compared with standards whenever possible. It was concluded that the results were in good agreement with the pharmacopoeial standards; therefore these herbal preparations are safe and effective for use.