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64886

SYNTHESIS OF SOME PYRIMIDINE DERIVATIVES OF EXPECTED BIOLOGICAL ACTIVITIES

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Last updated: 25 Dec 2024

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Abstract

A series of 4-substituted pyrimidines and fused pyrimidine ring system e.g. pyrido[2,3-d] pyrimidine were synthesized and the antitumor activity have been carried out for 8 compounds. Compound 4a also, which carries the pharmacophoric group IDA was tested for the hepatobilliary imaging effect.

DOI

10.21608/bfsa.2005.64886

Authors

First Name

Wafaa

Last Name

Zaghary

MiddleName

A.

Affiliation

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Helwan University, Cairo, Egypt

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Orcid

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First Name

Aida

Last Name

El-Azzouny

MiddleName

A.

Affiliation

Department of Pharmaceutical Sciences, National Research Center, Dokki, Giza

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City

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Orcid

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First Name

Mohammed

Last Name

Motaleb

MiddleName

A.

Affiliation

Hot Labs. Center, Atomic Energy Authority, Cairo, Egypt

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City

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Orcid

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First Name

Mohammed

Last Name

Kedr

MiddleName

A.

Affiliation

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Helwan University, Cairo, Egypt

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-

Orcid

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Volume

28

Article Issue

1

Related Issue

9815

Issue Date

2005-06-01

Receive Date

2004-07-21

Publish Date

2005-06-30

Page Start

17

Page End

25

Print ISSN

1110-0052

Online ISSN

3009-7703

Link

https://bpsa.journals.ekb.eg/article_64886.html

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https://bpsa.journals.ekb.eg/service?article_code=64886

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3

Type

Original Article

Type Code

1,096

Publication Type

Journal

Publication Title

Bulletin of Pharmaceutical Sciences Assiut University

Publication Link

https://bpsa.journals.ekb.eg/

MainTitle

SYNTHESIS OF SOME PYRIMIDINE DERIVATIVES OF EXPECTED BIOLOGICAL ACTIVITIES

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Article

Created At

22 Jan 2023