Fractionation and purification of the methanolic extract of the leaves of Spathodea campanulata P. Beauvais cultivated in Egypt afforded six compounds identified as: 1-Ocaffeoyl -D-glucopyranoside (1), kaempferol 3-O-(2-O -D-xylopyranosyl) -D-galactopyranoside (2), kaempferol 3-O-(6-O -L-rhamnopyranosyl) -D-galactopyranoside (3), acteoside (4), kaempferol 3-O-(6-O -L-rhamnopyranosyl) -D-glucopyranoside (5) and quercetin 3-O-(2-O -D-xylopyranosyl) -D-galactopyranoside (6). The structures of the isolated compounds were determined by physical, chemical and spectroscopic methods. All these compounds have been isolated for the first time from the genus spathodea