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176111

The Effects of Sub-lethal Concentrations of Sodium Fluoride on the Number and Diameters of Ovarian Follicles

Article

Last updated: 04 Jan 2025

Subjects

-

Tags

Pathology and clinical pathology

Abstract

Fluoride was the first compound utilized in the fluoridation of drinking water, and still used today t0 for prevent dental caries, sodium fluoride exerts it toxic effects on a different organs . Ovarian follicle considering a fundamental unit of ovary . Objective: the current work aimed to study the toxic effects of sodium fluoride (NaF) on the number and diameters of ovarian follicles . Materials and methods: three groups of adults female albino rats were used .The 1st group as untreated group, 2nd group was treated with 150ppm of sodium fluoride by gavage daily for 90 days, and the third group was treated with sodium fluoride (300ppm) by gavage daily for 90 days. Result :The sodium fluoride had an adverse effects on the number and diameters of ovarian follicle in both concentrated groups dosed group in contrast to the control group, also in addition to inhibit the maturation of ovarian follicle. These results suggest that sodium fluoride damage the structures of ovary, and has adverse effects on the coefficient of the female reproductive system

DOI

10.21608/javs.2021.74681.1077

Keywords

albino rats, dental caries, diameters, Fluoridation, ovarian follicle, Sodium fluoride

Authors

First Name

Hadeel

Last Name

Al-sabawy

MiddleName

B.

Affiliation

Department of pathology and poultry disease, Collage of Veterinary Medicine ,University of Mosul, Iraq.

Email

hadeelbasim2006@gmail.com

City

Mosul

Orcid

0000-0001-8077-0854

First Name

Bushra

Last Name

I. AL-Kaisie

MiddleName

-

Affiliation

Department of pathology and poultry disease, Collage of Veterinary Medicine ,University of Baghdad, Iraq.

Email

-

City

-

Orcid

-

Volume

6

Article Issue

3

Related Issue

24871

Issue Date

2021-07-01

Receive Date

2021-04-30

Publish Date

2021-07-01

Page Start

20

Page End

24

Print ISSN

1687-4072

Online ISSN

2090-3308

Link

https://javs.journals.ekb.eg/article_176111.html

Detail API

https://javs.journals.ekb.eg/service?article_code=176111

Order

3

Type

Original Article

Type Code

1,095

Publication Type

Journal

Publication Title

Journal of Applied Veterinary Sciences

Publication Link

https://javs.journals.ekb.eg/

MainTitle

The Effects of Sub-lethal Concentrations of Sodium Fluoride on the Number and Diameters of Ovarian Follicles

Details

Type

Article

Created At

22 Jan 2023