This study was conducted on 40 cows suffering from inactive ovaries brought to the Teaching Veterinary clinic of College of Veterinary, University of Mosul. The inactive ovary was diagnosed in 40 cows depending on the case's date and general examination by rectal palpation to determine the ovarian size and the existence of certain ovarian structures and check the uterine horns and body. The animals were divided following the identification of the affected animals with inactive ovaries, into two groups, each group composed of 20 cows. The animals in the first group were treated with GnRH hormone at a dose of 0.5 mg. In contrast, animals in the second group were treated by the ovaries' manual massage method via rectal palpation. The study findings clarified that the estrous response ratio amounts to 50% in the first group and 60% in the second group. Statistically, there were no differences in response ratio between the two groups in relation to the response.