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62668

Detection Limits Of Live Attenuated Poultry Viral Vaccine Testing Method For Detection Of Bacterial Contamination

Article

Last updated: 04 Jan 2025

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Subjects

-

Tags

Immunology and Vaccinology

Abstract

A total number of 27 vaccine vials including 3 batches of 3 different types of live attenuated poultry viral vaccines (tissue culture Gumboro vaccine, egg adapted colored ILT vaccine and egg adapted non colored ILT vaccine) were experimentally contaminated with 1,5,10 CFU of Salmonella typhimurium reference strain/dose then subjected for sterility testing as referenced in OIE. Further dilution was carried out of vaccines showing negative results. The results of statical analysis showed that there is a significant difference between direct inoculation of the vaccines and their dilutions. It could be concluded that the applied testing method is appropriate for testing sterility of living attenuated poultry viral vaccines but testing of some of such vaccines need further dilutions to obtain accurate results.

DOI

10.21608/javs.2019.62668

Keywords

Bacterial contamination, Detection limits, live attenuated vaccines

Authors

First Name

Hanan

Last Name

Ibrahim

MiddleName

M.

Affiliation

Central Laboratory for Evaluation of Veterinary Biologics (CLEVB)El-Seka El-Baida, Abbasia, Cairo, Egypt

Email

-

City

-

Orcid

-

First Name

Hanan

Last Name

Ahmed

MiddleName

A.

Affiliation

Central Laboratory for Evaluation of Veterinary Biologics (CLEVB)El-Seka El-Baida, Abbasia, Cairo, Egypt

Email

-

City

-

Orcid

-

First Name

Nourhan

Last Name

Nagy

MiddleName

-

Affiliation

Central Laboratory for Evaluation of Veterinary Biologics (CLEVB)El-Seka El-Baida, Abbasia, Cairo, Egypt

Email

nouranagy74@yahoo.com

City

-

Orcid

-

First Name

Gina

Last Name

Mohamed

MiddleName

M.

Affiliation

Central Laboratory for Evaluation of Veterinary Biologics (CLEVB)El-Seka El-Baida, Abbasia, Cairo, Egypt

Email

-

City

-

Orcid

-

First Name

Shafai

Last Name

S.M

MiddleName

-

Affiliation

Central Laboratory for Evaluation of Veterinary Biologics (CLEVB)El-Seka El-Baida, Abbasia, Cairo, Egypt

Email

-

City

-

Orcid

-

First Name

Aly

Last Name

A.M

MiddleName

-

Affiliation

Central Laboratory for Evaluation of Veterinary Biologics (CLEVB)El-Seka El-Baida, Abbasia, Cairo, Egypt

Email

-

City

-

Orcid

-

Volume

4

Article Issue

1

Related Issue

9406

Issue Date

2019-04-01

Receive Date

2019-02-10

Publish Date

2019-04-01

Page Start

1

Page End

4

Print ISSN

1687-4072

Online ISSN

2090-3308

Article File

JAVS_Volume 4_Issue 1_Pages 1-4.pdf

PDF . 273.6kB

Link

https://javs.journals.ekb.eg/article_62668.html

Detail API

https://javs.journals.ekb.eg/service?article_code=62668

Order

1

Type

Original Article

Type Code

1,095

Publication Type

Journal

Publication Title

Journal of Applied Veterinary Sciences

Publication Link

https://javs.journals.ekb.eg/

MainTitle

Detection Limits Of Live Attenuated Poultry Viral Vaccine Testing Method For Detection Of Bacterial Contamination

Details

Type

Article

Created At

22 Jan 2023