The availability of abundant Spectrum resources, power consumption and inter cell interference can be assumed as a bulky challenges towards meeting the high capacity demands and coverage resources expected in fifth-generation 5G technologies. By integrating Millimeter wave (mm-wave) into 5G technologies, allowing a huge number of links can be transmitted concurrently by reusing the same spectrum and providing a high density of access nodes. Also, flexible backhauling and access wireless links can be considered for heterogeneous access 5G technologies with a high directional antenna arrays. The scheme proposed in this paper can significantly enhance network throughput in mm-wave 5G heterogeneous networks by utilizing a genetic based algorithm GA for optimally power and radio resources management based on spectrum sharing with time and space-division multiple access. The proposed algorithm allows backhaul and access links with /without conflicting flows to be transmitted simultaneously without/with interference. Through a comprehensive simulations, we show that the proposed genetic algorithm achieves significant enhancement in terms of user throughput and resources utilization.