Bioinformatics means the analysis of biological information using
computers and statistical techniques. This paper presents the linear
spectral estimation techniques based on DFT that applied for the
analysis of deoxyribonucleic acid (DNA) sequence. These methods
are useful frequency domain presentation techniques which
improve the analysis of DNA sequence. The representation of DNA
sequence in frequency domain is useful to extract some desirable
information which cannot be extracted from the time domain
analysis of that sequence. In addition, this paper investigates the
location of exon in DNA sequences using linear spectral estimation
techniques for gene prediction in DNA sequences in exon. A
comparison study between all these linear spectral estimation
techniques is performed.