Interdisciplinary and applied studies are the most common feature now on scientific research and scientific thinking, and even impose themselves in the contemporary world and impose trends and ideas that emphasize the unity of knowledge and the importance of interdisciplinary integration, it was necessary to use one of them to take on a research and presented in the light of knowledge and a new theory. Science fiction literature is still a modern literature that attracted different age groups and different intellectual properties. Science fiction literature was cooperated between fantasy literature and science, which have been in conflict and doesn't have long-standing reconciliation, Interdisciplinary study gave them integration and union.  She reduced sharpness of science, dryness and lack of imagination and took a lot of fantasy literature and it was accepted by the public, Fantasy literature has benefited from the revolution of science and changed its style in a new color that offers a scientific fact confirmed by fertile imagination. Thus, science fiction literature is reproduced, new Literary genre serves human at the same time the world benefits from it. in this paper I presented the content of the interdisciplinary Study and its application between fantasy literature and science, a simple definition of science fiction literature, its functions, types, characteristics, presentation of works dealing with this literature genre (medicine Cryonics theory for “Time lord" for Nehad Sherif and elativity and the fourth dimension in physics for “Three bodies" for Liu Ci Xin). Finally I gave a small outlook for science fiction literature future.