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115879

EXPRESSION OF CONNEXINE 43 IN THE SEMINIFEROUS EPITHELIUM OF WHITE MICE DURING TESTICULAR ONTOGENESIS: IMMUNOHISTOCHEMISTRY AND IN SITU HYBRIDIZATION

Article

Last updated: 25 Dec 2024

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Subjects

-

Tags

Veterinary Anatomy, Histology and Physiology “Veterinary Academic Studies".

Abstract

Immunohistochemistry and in situ hybridization were used to elucidate the distribution of connexine43 (Cx43) protein and its mRNA in mice seminiferous epithelium during testicular ontogenesis. Cx43 protein expresses itself in mice male gonads as early as the premordia germ cells reach the gonadal blastema at 12 days postcoitum (dpc) indicating its importance in testicular development. It was expressed mainly in the basal portions of testicular cords throughout pre- and postnatal periods of gonadal development. Cx43 mRNA was expressed more strongly in germ cells than in supporting cells. Cx43 protein expression was found to be stage dependant being expressed strongly in stage VII (which is characterized by retraction of the main bulk of Sertoli cells to basal locations allowing better visualization of the inter Sertoli cell junction complexes which represent the main site of Cx43 expression)

DOI

10.21608/kvmj.2007.115879

Keywords

Immunohistochemistry, in situ hybridization, connexine43 (Cx43) protein

Authors

First Name

Ahmed E.

Last Name

Zayed

MiddleName

-

Affiliation

Department of Anatomy and Histology, Faculty of Veterinary Medicine, Assiut University, Egypt. Department of Urology and Pediatric Urology, University of Giessen, Germany.

Email

-

City

-

Orcid

-

First Name

Mona A.

Last Name

Ali

MiddleName

-

Affiliation

Department of Anatomy and Histology, Faculty of Veterinary Medicine, Kafrelshaikh University, Egypt.

Email

-

City

-

Orcid

-

First Name

Amin

Last Name

Hassanin

MiddleName

-

Affiliation

Department of Anatomy and Histology, Faculty of Veterinary Medicine, Kafrelshaikh University, Egypt.

Email

-

City

-

Orcid

-

First Name

Anne

Last Name

Hild

MiddleName

-

Affiliation

Institute of Anatomy, Histology and Embryology, University of Giessen, Germany

Email

-

City

-

Orcid

-

First Name

Ralph

Last Name

Brehm

MiddleName

-

Affiliation

Institute of Anatomy, Histology and Embryology, University of Giessen, Germany

Email

-

City

-

Orcid

-

First Name

Klaus

Last Name

Steger

MiddleName

-

Affiliation

Institute of Anatomy, Histology and Embryology, University of Giessen, Germany

Email

-

City

-

Orcid

-

Volume

5

Article Issue

1

Related Issue

16824

Issue Date

2007-04-01

Receive Date

2007-01-01

Publish Date

2007-04-01

Page Start

180

Page End

194

Print ISSN

1687-1456

Online ISSN

2682-2954

Article File

KVMJ_Volume 5_Issue 1_Pages 180-194.pdf

PDF . 1.1MB

Link

https://kvmj.journals.ekb.eg/article_115879.html

Detail API

https://kvmj.journals.ekb.eg/service?article_code=115879

Order

11

Type

Original Article

Type Code

1,064

Publication Type

Journal

Publication Title

Kafrelsheikh Veterinary Medical Journal

Publication Link

https://kvmj.journals.ekb.eg/

MainTitle

EXPRESSION OF CONNEXINE 43 IN THE SEMINIFEROUS EPITHELIUM OF WHITE MICE DURING TESTICULAR ONTOGENESIS: IMMUNOHISTOCHEMISTRY AND IN SITU HYBRIDIZATION

Details

Type

Article

Created At

22 Jan 2023