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114179

EFFICACY OF A NEW ISOLATE RABBIT HEMORRHAGIC DISEASE VIRUS VACCINE

Article

Last updated: 25 Dec 2024

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Subjects

-

Tags

Veterinary Medicine and Infectious Diseases “Veterinary Diseases".

Abstract

The present study was carried out to prepare and evaluate an inactivated vaccine from new isolate rabbit hemorrhagic disease (RHD) virus that causes outbreaks in rabbit flocks vaccinated with commercially available vaccines. Sixty, 3 months old New Zealand rabbits were allotted into four groups (A, B, C, D). Groups A, B, C were vaccinated subcutaneously with the new isolate of RHD virus vaccine, Izovac Mevax and SVRI vaccines respectively. Group D was kept as unvaccinated control. All rabbits were challenged at 10 days post vaccination by intranasal inoculation. Rabbits in all groups were observed daily for clinical signs and mortalities. Hemagglutination inhibition titers, hematological, biochemical and histopathological changes were studied throughout the experimental period. Immunological response and resistance to challenge were highest in group A which was vaccinated with the new isolate RHD virus vaccine, meanwhile rabbits in this group maintained a good general health status as reflected by biochemical and hematological pictures. According to these findings, the new isolate RHD virus vaccine is strongly recommended to minimize economic losses that RHD virus outbreaks can produce in industrial rabbitries.

DOI

10.21608/kvmj.2006.114179

Keywords

rabbit hemorrhagic disease, inactivated vaccine

Authors

First Name

A. Y.

Last Name

Metwally

MiddleName

-

Affiliation

Animal Health Research Institute, Kafr El-Sheikh Prov. Laboratory

Email

-

City

-

Orcid

-

First Name

M. M .

Last Name

Ismail

MiddleName

-

Affiliation

Department of Poultry and Fish, Faculty of Veterinary Medicine, Kafrelsheikh University,

Email

-

City

-

Orcid

-

First Name

A. M.

Last Name

Hegazy

MiddleName

-

Affiliation

Animal Health Research Institute, Kafr El-Sheikh Prov. Laboratory.

Email

-

City

-

Orcid

-

First Name

H. A.

Last Name

Soliman

MiddleName

-

Affiliation

Animal Health Research Institute, Kafr El-Sheikh Prov. Laboratory.

Email

-

City

-

Orcid

-

Volume

4

Article Issue

2

Related Issue

16573

Issue Date

2006-10-01

Receive Date

2006-09-01

Publish Date

2006-10-01

Page Start

45

Page End

58

Print ISSN

1687-1456

Online ISSN

2682-2954

Article File

KVMJ_Volume 4_Issue 2_Pages 45-58.pdf

PDF . 602.1kB

Link

https://kvmj.journals.ekb.eg/article_114179.html

Detail API

https://kvmj.journals.ekb.eg/service?article_code=114179

Order

4

Type

Original Article

Type Code

1,064

Publication Type

Journal

Publication Title

Kafrelsheikh Veterinary Medical Journal

Publication Link

https://kvmj.journals.ekb.eg/

MainTitle

EFFICACY OF A NEW ISOLATE RABBIT HEMORRHAGIC DISEASE VIRUS VACCINE

Details

Type

Article

Created At

22 Jan 2023