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113533

THE EFFECT OF DICLAZURIL AND MADURAMICIN ALONE OR TOGETHER IN CONTROLLING CECAL COCCIDIOSIS IN CHICKENS

Article

Last updated: 25 Dec 2024

OverviewSimilar Items

Subjects

-

Tags

Veterinary Pharmacology, Toxicology and Forensic Medicine.

Abstract

Coccidiosis in chicken farms are considered as one of the most serious problems affecting both small and large poultry producers. Eimeria tenella now is consider as one of the most pathogenic and important Eimeria species affecting about 90% of intensive broiler production. This study was carried out to evaluate the efficacy of maduramicin (5ppm), diclazuril (2.5ppm) and both drugs together on healthy and experimentally infected chicken with E.tenella (50000 sporulated oocyst) on 15th  day of age after the symptoms of infection had appeared on 5th day of infection for 3 successive days from 20th day to 22nd  day and from 30th day to 32nd day of age. The results revealed that the infected group treated with both of maduramicin and diclazuril did not show any antagonistic interaction between them but leading to the best results among all infected treated groups by overcome clinical signs, decrease mortality rate, lesion scoring, give the lowest count of oocyst shedding and represented the best improvement in biochemical parameters throughout the experiment. This reflects the synergistic interaction between them without any significant adverse effect. The efficacy of diclazuril was superior to maduramicin in treatment of cecal coccidiosis by marked improvement on cecal integrity and reduction of the oocyst shedding. Non infected treated groups did not show any significant difference than negative control group during the experimental period and this reflects the safe use of both drugs either individually or together

DOI

10.21608/kvmj.2011.113533

Keywords

coccidiosis, chicken, maduramicin, diclazuril

Authors

First Name

M. I.

Last Name

Abd El- Aziz

MiddleName

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Affiliation

Pharmacology Department, Fac. Vet. Med. Kafrelsheikh University

Email

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City

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Orcid

-

First Name

K. A.

Last Name

El Shazly

MiddleName

-

Affiliation

Pharmacology Department, Fac. Vet. Med. Kafrelsheikh University

Email

-

City

-

Orcid

-

First Name

Eman, M. E.

Last Name

El Sherbeney

MiddleName

-

Affiliation

Directorate of Veterinary Medicine in Gharbia

Email

-

City

-

Orcid

-

Volume

9

Article Issue

1

Related Issue

16459

Issue Date

2011-04-01

Receive Date

2011-01-01

Publish Date

2011-04-01

Page Start

161

Page End

187

Print ISSN

1687-1456

Online ISSN

2682-2954

Article File

KVMJ_Volume 9_Issue 1_Pages 161-187.pdf

PDF . 829.6kB

Link

https://kvmj.journals.ekb.eg/article_113533.html

Detail API

https://kvmj.journals.ekb.eg/service?article_code=113533

Order

7

Type

Original Article

Type Code

1,064

Publication Type

Journal

Publication Title

Kafrelsheikh Veterinary Medical Journal

Publication Link

https://kvmj.journals.ekb.eg/

MainTitle

THE EFFECT OF DICLAZURIL AND MADURAMICIN ALONE OR TOGETHER IN CONTROLLING CECAL COCCIDIOSIS IN CHICKENS

Details

Type

Article

Created At

22 Jan 2023