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110166

INFLUENCE OF TOPICAL BROWN ALGAE (CYSTOSEIRA MYRICA) EXTRACT APPLICATION ON WOUND HEALING IN RATS

Article

Last updated: 04 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

Veterinary Surgery and Theriogenology.

Abstract

Objectives:To investigate the feasibility and safety of brown algae (Cystoseira myrica) extract in the improvement of wound healing process.
Materials and Method:Full thickness excision wounds (1.5 x 1.5 cm) were created under general anesthesia on the back of the rats. These rats were divided into two groups; control group (Group C) and brown algae extract topical application group (Group B). Each wound area was measured on days 0, 3, 6, 9, 12, 15 and 18 post-wounding. On day 18 post-wounding, animals were sacrificed.  Quantification of granulation tissue and their biochemical and histological aspects in control as well as treated groups were estimated.
Results: Brown algae extract showed significant increase in wound contraction and formation of scars on days 9, 12, 15 and18 post wounding (p < 0.001). Histologically, extracellular matrix deposition and epithelialization were promoted in Group B.
Conclusion: The present results suggest that brown algae (Cystoseira myrica) extract can effectively improve wound healing in a full-thickness skin wound model. Use of brown algae (Cystoseira myrica) extract might therefore facilitate development and improvement of wound healing treatments in future.

DOI

10.21608/kvmj.2013.110166

Keywords

Brown Algae, Cystoseira myrica, skin, Wound healing

Authors

First Name

Ayman

Last Name

Atiba

MiddleName

-

Affiliation

Departments of Surgery, Anaesthesiology and Radiology, Faculty of Veterinary Medicine, Kafrelsheikh University, Egypt.

Email

-

City

-

Orcid

-

First Name

Walied

Last Name

Abdo

MiddleName

-

Affiliation

Department of Veterinary Pathology, Faculty of Veterinary Medicine, Kafrelsheikh University, Egypt.

Email

waliedsobhy@yahoo.com

City

-

Orcid

-

First Name

Fedekar F.

Last Name

Madkour

MiddleName

-

Affiliation

Marine Science Department, Faculty of Science, Port Said University, Egypt.

Email

-

City

-

Orcid

-

Volume

11

Article Issue

1

Related Issue

16457

Issue Date

2013-04-01

Receive Date

2013-01-01

Publish Date

2013-04-01

Page Start

79

Page End

90

Print ISSN

1687-1456

Online ISSN

2682-2954

Article File

KVMJ_Volume 11_Issue 1_Pages 79-90.pdf

PDF . 598.3kB

Link

https://kvmj.journals.ekb.eg/article_110166.html

Detail API

https://kvmj.journals.ekb.eg/service?article_code=110166

Order

5

Type

Original Article

Type Code

1,064

Publication Type

Journal

Publication Title

Kafrelsheikh Veterinary Medical Journal

Publication Link

https://kvmj.journals.ekb.eg/

MainTitle

INFLUENCE OF TOPICAL BROWN ALGAE (CYSTOSEIRA MYRICA) EXTRACT APPLICATION ON WOUND HEALING IN RATS

Details

Type

Article

Created At

22 Jan 2023