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109559

EFFECT OF CAMEL MILK ON DIABETIC NEPHROPATHY IN STREPTOZOTOCIN – INDUCED DIABETIC RATS

Article

Last updated: 25 Dec 2024

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Subjects

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Tags

Veterinary Anatomy, Histology and Physiology “Veterinary Academic Studies".

Abstract

Diabetic nephropathy is one of the microvascular complications of diabetes mellitus. It is a life-threatening complication and occurs in 20-40% of patients suffering from diabetes and it is the single leading cause of end stage renal disease (ESRD). This present study was designed to explore the efficiency of she camel milk or buffalo milk  in controlling  diabetic nephropathy . Eighty male albino rats were used in this study, divided into four groups; one group was used as a normal control group, while the remaining three groups were injected with streptozotocin in order to induce diabetes. The diabetic group was divided into Diabetic Control Group (DCG), she camel milk group (CMG) and buffalo milk group (BMG),and treated with she camel milk and buffalo milk  for 4 weeks. Blood glucose was measuredweekly, microalbuminuria was measured at the 4th weekand histopathological study was made at the 1st and the 4th week for measuring the Glomerularsclerosis index. This study revealed thatthere was a significant decrease in blood glucose of CMG than BMG. She camel milk group exhibited a significant improvement in microalbuminuria compared to diabetic control animals and ameliorate the pathological changes induced by diabetes. This study documented the efficiency of she camel milk in controlling of diabetic nephropathy and improvement of kidney function. The mechanism of this effect is still unknown, so an extensive research on she camel milk is still needed to demonstrate this mechanism

DOI

10.21608/kvmj.2015.109559

Keywords

diabetic nephropathy, she camel milk, Microalbuminuria

Authors

First Name

Ibrahim

Last Name

Fattouh

MiddleName

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Affiliation

Department of Biochemistry, Faculty of Veterinary Medicine, Kafrelsheikh University, Egypt

Email

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City

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Orcid

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First Name

Sabreen

Last Name

Ezzat

MiddleName

-

Affiliation

Department of Biochemistry, Animal health research institute, Kafr El-Sheikh branch ,Dokki ,Egypt.

Email

-

City

-

Orcid

-

First Name

Shireen

Last Name

Soliman

MiddleName

-

Affiliation

Department of Biochemistry, Animal health research institute, Kafr El-Sheikh branch ,Dokki ,Egypt.

Email

-

City

-

Orcid

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Volume

13

Article Issue

1

Related Issue

16443

Issue Date

2015-04-01

Receive Date

2015-01-01

Publish Date

2015-04-01

Page Start

71

Page End

85

Print ISSN

1687-1456

Online ISSN

2682-2954

Article File

KVMJ_Volume 13_Issue 1_Pages 71-85.pdf

PDF . 953.7kB

Link

https://kvmj.journals.ekb.eg/article_109559.html

Detail API

https://kvmj.journals.ekb.eg/service?article_code=109559

Order

5

Type

Original Article

Type Code

1,064

Publication Type

Journal

Publication Title

Kafrelsheikh Veterinary Medical Journal

Publication Link

https://kvmj.journals.ekb.eg/

MainTitle

EFFECT OF CAMEL MILK ON DIABETIC NEPHROPATHY IN STREPTOZOTOCIN – INDUCED DIABETIC RATS

Details

Type

Article

Created At

22 Jan 2023