Background: Egypt is the 8th in order among the top 10 countries for the number of adults with diabetes; estimated prevalence is 17.3% in 2017.Obesity is a chronic disease characterized by excessive accumulation of body fat and associated with the development of comorbidities such as diabetes mellitus, hypertension and dyslipidemia. It is associated with changes in zinc metabolism, which are characterized by reduced plasma concentrations. Zinc may regulate serum leptin concentration and appetite control. Objective: This study was conducted to assess the effect of zinc supplementation on BMI (body mass index) in type 2 diabetics. Methods:  It was a single blinded, randomized, placebo-controlled trial. Patients (n=200) were randomly allocated into two groups: zinc group, & placebo group, zinc supplementation was given for 12 weeks. Body mass index (BMI) was assessed at baseline & after 12 weeks.                                           
Results: There was no statistically significant difference in BMI in zinc group compared to placebo group after 12 weeks. Conclusion: Zinc supplementation has no beneficial effect on body mass index in type 2 diabetic patients.