Background: Availability of prenatal care, has played a part in reducing maternal and neonatal death rates. The WHO recommends that pregnant women should receive four antenatal care visits to be complier. Objectives: This study was conducted to assess compliance of pregnant women with antenatal care services. Also, it aimed to determine factors affecting it. Methods: A cross-sectional study was conducted on 330 pregnant women in third trimester, aged from 18 to 45 years old attending Tanta Family Health Centre and Unit for antenatal care during period from April 2017 June 2017.The data was collected by a predesigned questionnaire which is consisted of: socio-demographic data, obstetric history and compliance of participants with ANC visits. Results: Pregnant women who were compliant were (49. 7%). Compliance was evident among women from urban area, who were 2ry educated & their husbands were moderately socioeconomic state. Predictive factors for ANC compliance were good doctor- patient relationships (OR 13.4), women's knowledge about high risk pregnancy (OR 10.6), risky symptoms during pregnancy (OR 9.8) , being sick (OR 5.2), gestational age of 8^th month (OR4.7) then presence of obstetric problems in previous& current pregnancies (OR 3.9 & 3.9 respectively).Conclusion: Prevalence of ANC compliance was 49.7%, Predictive factors for ANC compliance were doctor- patient relationships, women's knowledge about high risk pregnancy, risky symptoms during pregnancy, being sick, gestational age of 8^th month then presence of obstetric problems in previous& current pregnancies